Quality Evaluation And Data Mining Of Clinical Literature Of Acupuncture

Objective:To establish the quality evaluation method and level of evidence suggest about clinical literature of acupuncture deqi. This study uses Data mining technique for different grade and levels of acupuncture deqi clinical documents based on literature quality evaluation to explore some deqi knowledge and provide documentation support of Acupuncture clinic and research,Methods:The quality evaluation method about clinical literature on acupuncture deqi was established by analyse the feature of acupuncture deqi clinical literature and EBM methods, combined with the characteristic of acupuncture research. High quality literature could be acquired by using this method. Excavated the acupuncture deqi literature via weka.Results:1. There are 191 clinical documents about acupuncture deqi published domestic and overseas during 1949.01-2016.03, which including 149 Chinese papers,42 English papers and 76 RCT papers,20 nRCT papers,24 case series papers,63 expertise papers,8 individual cases papers.2. The quality evaluation method about clinical literature on acupuncture deqi include evaluate the evidence of "Deqi" and general characteristics of literature.3. The evidence grade of Acupuncture Deqi clinical literature suggests that grade I means high quality of "Deqi" evidence puls high quality of documentary evidence, grade II means high quality of "Deqi" evidence puls low quality of documentary evidence, grade III means low quality of "Deqi" evidence puls high quality of documentary evidence, grade IV means low quality of "Deqi" evidence puls low quality of documentary evidence.4. After quality evaluation, there are 24 papers about grade 1,13 papers about grade Ⅱ,59 papers about grade Ⅲ,95 papers abou grade Ⅳ.5. Comprehensive considering the deqi and documentary evidence, the high quality literature in this study as grade Ⅰa、Ⅰb、Ⅱa、Ⅱb、Ⅲa、Ⅲb.6. Results of data mining:6.1 There are 56 studies on the relationship between deqi and effectiveness, including 41 high quality studies. There are 33 studies consider that deqi related to the effect, support for 80.5%,and 8 studies consider deqi unrelated to the effect, support for 19.5%.The support of deqi related to the effect much higher than deqi unrelated to the effect. The result of deqi unrelated to the effect mainly comes from English documents.6.2 There are 111 studies about the relationship between the characteristics of deqi and effectiveness. There are 65 studies think that conduction good for effect. The relationship between intensity of deqi and effectiveness mainly related to the diseases. The results of associative analysis prompt that warm sesation and positively correlated with the effect is the strong association rule. There are only 16 high quality studies, including 8 studies consider that conduction good for effect. The results of associative analysis prompt that strong sesation and deep needling correlated with the effect are the strong association rules.6.3 There are 22 studies on Acupuncture Deqi treat dysmenorrhea, including 9 studies about the relationship between deqi or not and effect, and 12 studies about the relationship between the characteristics of deqi and effectiveness. These 9 studies all think deqi related to the effect. Conduction is positively correlated with the effect appears most frequently. The commonly used points were SP6,RN4,ST36,RN6 and SP8.The most commonly used acupoints combination was RN4 and SP6.6.4 There are 12 studies on Acupuncture Deqi treat facial paralysis, including 6 studies about the relationship between deqi or not and effect, and 6 studies about the relationship between the characteristics of deqi and effectiveness. These 6 studies all think deqi related to the effect. Weak needling sensation connect with valid effect have higher support. High quality studies consider that strong needling sensation have valid effect.6.5 There are 81 studies on Acupuncture Deqi treat pain syndrome, about 70 percent of the study indicated that deqi related to the effect, others thought that deqi unrelated to the effect. Conduction is positively correlated with the effect appears most frequently.6.6 Acpoints of ST36,LI4,LI11,LI15,GB34 and Yangming Meridian were commonly used while disease of stroke. The most commonly used acupoints combination was LI15 and ST36.6.7 Brain function, peripheral blood, EEG and EMG were often used as objective indexes about deqi.Conclusion:1. This research initially estabished quality evaluation method about clinical literature on acupuncture deqi.2. Through this method, we found that the quality of literature about acupuncture deqi needed to improve. Clinical studies simply evaluate the evidence of "deqi". Expertise literature is lack of continuity and integrity.3. The mining results show that most studies approve deqi related to the effect. Few studies think that deqi unrelated to the effect, which have the study bias of different diseases,deqi evaluation method and acpoints. The relationship between intensity of deqi and effectiveness mainly related to the diseases. Deqi could improve the effect while the diseases of facial paralysis and stroke were treated by acupuncture. The relationship between radiating sensation and effect has widely researched, and the most results thought that radiating sensation has good effect. Few studies discuss the relationship between deqi and effect in the same disease, besides, they have low quality. These factors affect the validity and accuracy of data mining in some degree.4. The variety of indexes of deqi can reflect the feeling of deqi in some extent, but the reliability need more research to verify.