| Objective: Now the incidence of obesity and type 2 diabetes mellitus (T2DM) rised year after year. Diabetes mellitus, hypertension, dyslipidemia, coronary heart disease, stroke often complicated with obesity were known as the "death Quintet", which had become an important human health hazards of non-communicable epidemic disease. Obesity was an independent risk factor of T2DM incidence. Obesity could cause insulin resistance (IR), insulin secre -tion disability and metabolic disorders. For obese patients with T2DM, weight lose was not only benefit to plasma glucose control, but also to reducing complications. Therefore raising awareness of obesity and T2DM, and researching its pathogenesis and preventions, had become an important social health problem. This study was to investigate the relationship between obesity and T2DM, and the influencing of hypertension, dyslipidemia and non-alcoholic fatty liver disease (NAFLD) by analyzing clinical data of 400 patients with T2DM.Methods: According to the body mass index (BMI), 400 patients with T2DM were divided into three groups-115 cases in normal weight group, 161 cases in overweight group and 124 cases in obese group. The heights and body weights were precisely measured, and BMI was calculated. The difference of blood pressure, blood lipids, NAFLD were compared among different groups.Results: The percentage of the patients with T2DM in normal weight group, overweight group, obese group respectively was 28.75%, 40.25% and 31.00%. The prevalence of hypertension (68.55%), dyslipidemia (54.83% ), NAFLD (50.00%) in obese group were significantly higher than those (43.48%,34.78%,13.04%) in normal weight group (all p<0.01) and those(54.66%,46.58%,23.60%) in overweight group (all p<0.01).Conclusions: 1 Obesity, the impontant risk factor, was correlated with a higher prevalence of T2DM.2 Gradual increased in metabolic disorders, such as blood pressure, dyslipidemia and NAFLD were seen as BMI increased in the studies. |
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