| objective:The subject of traditional Chinese medicine, based on the overall concepts and principles of disease in this, through the salvia miltiorrhiza injection point injection therapy female Qi stagnation blood stasis type melasma the clinical observation, understanding point injection therapy for melasma treatment system and the theory of dialectical further clarify the efficacy of this treatment of melasma and advantages, and associated symptoms observed in patients with melasma improvement, clinical treatment for the future provide an objective basis for melasma.Methods:The subjects were 80 cases of patients from January 2009 to March 2010 to Wuhan Hospital of Integrated Chinese and Western medicine specialist out-patient clinic dermatologist chloasma chloasma patients of Qi stagnation blood stasis type, and meet diagnostic criteria and exclusion criteria.Patients were randomly divided into two groups:treatment group 40 cases, oral Shugan Huayu Freckle Decoction bilateral Zusanli point injection salvia injection, each point lml, once a week, four times as a course (one month), continuous treatment of 3 courses. The control group of 40 patients, oral Shugan Huayu Freckle Decoction,1 month for a course of treatment,were treated for 3 courses.Note that sunscreen during treatment for all patients,outside the rub titanium dioxide frost during the day (outdoor workers, once every two hours), evening outside the rub SOD arbutin acid cream (these two are for external use in our hospital from pharmaceuticals). To disable internal and external medicine during treatment 3 months after treatment, compared the change of two groups of lesions before and after treatment area, skin lesions fall colors, and symptom score reducing index, and observe the distention and pain in the chest and hypochondriac region, irritability, irregular menstruation, or dysmenorrhea and other associated symptoms that may occur to improve the situation, as well as adverse reactions.Results:The number of statistical analysis confirmed that the two groups before treatment in patients with age, duration,lesion site classification, lesion symptom score,with no significant difference in symptom score, with comparable(P>0.05).After the treatment effect observed after three months, both groups showed significant symptom improvement of skin lesions after treatment than before treatment points are decreased after treatment, improvement in disease severity compared with the control group was significantly (P<0.05); 40 cases of treatment group, the basic cured 7 cases, effective in 16 cases, improvement in 9 cases, invalid in 8 cases, markedly effective rate was 57.5%, the total effective rate was 80.0%; 40 cases of control group, the basic cured three cases, effective in 12 cases, improvement in 12 cases and invalid in 13 cases, markedly effective rate was 37.5%, total effective rate was 67.5%. Difference between the two groups was significant, the treatment group is superior to the control group (P<0.05). Two groups of patients with symptoms of varying degree of improvement, the treatment group for the distention and pain in the chest and hypochondriac region and irregular menstruation or dysmenorrhea improving effect better than the control group (P<0.05). In the course of treatment, both groups had no obvious side effects.Conclusion:Two groups of melasma skin lesions were improved, but the efficiency of the treatment group was significantly better than the control group, indicating point injection therapy can significantly improve the clinical efficacy of chloasma. Both for patients with melasma symptoms were significantly improved with the role,but the treatment group with the characteristics of high efficacy. |