Research In Asthenia And Sthenia Of HIV/AIDS By Infrared Imaging Technology

1 ObjectiveIn the guidance of fundamental theory of TCM, through comparing zang fu's thermal parameters (△T) and heat sequence of HIV infected people, AIDS patients and healthy people presume the functions of zang fu of HIV/AIDS group and try to explore the methods of syndrome differentiation of AIDS in using of infrared imaging technology.2 Methods2.1 MethodsDesign is retrospective case-control study. Selecting a number of people to fill in the physique questionnaire of Chinese medicine and informed consent form, and accept the infrared imaging test at the same time. According to results of the physique questionnaire of Chinese medicine, we determine those persons whose transformation scores are more than sixties and transformation scores of other eight physique less than thirties as healthy group.All subjects that received infrared imaging detection use a unified automated analytical instruments, we collect two infrared images of ventral aspect and dorsal aspect, and relative temperature of triple energizer, heart, liver, spleen, lung, kidney, stomach, small intestine, large intestine, urinary bladder, the governor vessel, conception vessel and shen que will be automatically calculated by computer.2.2 InstrumentCamera lens:pixel 320*240, spectrum 8～14μm, resolving power 0.08℃, precision±1℃, focal lenth 0.5-6m, testing extent 20～40℃2.3 SubjectsAll the healthy group come from Beijing area, total 325 cases, and 72 cases are female; average age 24.17±4.634, those are no disease and whose transformation scores are more than sixties and transformation scores of other eight physique less than thirties as healthy group.HIV/AIDS people come from Beijing, Liuzhou and Shanghai, total of 273 cases, among them, HIV infected people are 165 cases with a average age of 35.47±10.169(119 males,46 females); AIDS patients are 108 cases with a average age of 37.09±8.755(83 males,25 females);2.4 Observation targetWe collect two infrared images of ventral aspect and dorsal aspect, and relative temperature of triple energizer, heart, liver, spleen, lung, kidney, stomach, small intestine, large intestine, urinary bladder, the governor vessel, conception vessel and shen que will be automatically calculated by computer.2.5 Statistical methodAll data import SPSS 13.0 statistical software package, measurement data are describe d with average±standard deviation; comparison of measurement data among groups use analysis of covariance, age as covariate; comparison of Count data among groups use Kruskal-wallis.3 Results3.1Comparison of Zang fu's metabolic heat within three group3.1.1 Triple energizerThe triple energizer metabolic heat of HIV infected people and AIDS patients is different from healthy group, upper energizer metabolic heat of HIV infected people and AIDS patients is excesser than healthy group, In contrast, middle and lower energizer are lower than healthy group.Meanwhile, AIDS patients is markly lower than HIV infected people in middle energizer according to the results of Analysis of covariance.The results of Comparison of Triple energizer's metabolic heat within three group show us that:Focus on the metabolism heat of AIDS patients was significantly lower than HIV infected people, the biological functions of middle energizer has been destroyed, while, because of qi and blood is produced by middle energizer, so we can infer that the function of defence of AIDS patients was even worse, vulnerable to committed by kinds of evils.3.1.2 The Five Zang-Organs The Five Zang-Organs metabolic heat of HIV infected people and AIDS patients is different from healthy group, The heart and lung metabolic heat of HIV infected people and AIDS patients is excesser than healthy group, Other organs are lower than healthy group.The results of Analysis of covariance show that:heart, liver, lung, kidney, life-gate of HIV infected people and AIDS patients are significantly different from helthy group(P<0.05), according to graph 2, metabolic heat of heart and lung of HIV infected people and AIDS patients show a ascending deviation, In contrast, liver, kidney, life-gate show a descending deviation.Meanwhile, in the comparison of HIV infected people and AIDS patients,there was significant difference in liver, spleen, kidney and life-gate, according to graph 2, the liver, spleen, kidney and life-gate of AIDS patients markly lower than HIV infected people.The results of Comparison of Five Zang-organs's metabolic heat within three group show us that:the functions of liver, kidney, life-gate of HIV/AIDS are markly lower than healthy group, more over, the functions of spleen, liver, kidney, life-gate of AIDS patients was significantly lower than HIV infected people, this results directly proof that AIDS is a disease that gradually deplet the body vitality. On metabolic heat of heart and lung, HIV/AIDS people are markly escesser than healthy group, this results maybe induced by kinds of infections or pathological aversion of body energies.3.1.3 The Six Fu-organsThe Six Fu-Organs metabolic heat of HIV infected people and AIDS patients is different from healthy group, The large intestine, small intestine, stomach, urinary bladder are markly lower than healthy group; stomach and nrinary bladder of AIDS patients are significant lower than HIV infected people.According to graph 3. metabolic heat of The large intestine, small intestine, stomach, urinary bladder of HIV infected people and AIDS patients show a descending deviation, in the comparison of HIV infected people and AIDS patients,there was significant difference in stomach, according to graph 3, the stomach of AIDS patients markly lower than HIV infected people. The results of Comparison of Six Fu-orangs's metabolic heat within three group show us that:the functions of stomach, small intestine, urinary bladder, large intestine of HIV/AIDS are markly lower than healthy group, showing that the decline of pepsic function.The results also tell us that protecting essential qi of the stomach is very important in treating AIDS.3.1.4The governor vessel conception vessel shen que pointThe healthy group is totally excesser than HIV infected people in governor vessel, conception vessel and shen que point, and HIV infected people is excesser than AIDS patients, there group shows no significant difference in governor vessel.According to graph 4, metabolic heat of shen que point of HIV infected people shows a descending deviation in comparison to healthy group. there is a significant difference in governor vessel and conception vessel between HIV infected people and AIDS patients, According to graph 4, the governor vessel and conception vessel are markly lower than HIV infected people.In addition, the thermal parameters of the governor vessel prompted to the decline of warm function, and the thermal parameters of Conception Vessel and Shenque point may be prompted to the heavier chill evil.3.2Comparison of Zang fu's heat sequence within three group3.2.1Triple energizerHeat sequence of Triple energizer of HIV infected people and AIDS patients is different from healthy group, the healthy group gradually gose more hotter from upper energizer to lower energizer, in contrast, HIV/AIDS shows a inversion heat sequence in Triple energizer.3.2.2The Five Zang-OrgansHeat sequence of The Five Zang-Organs of HIV infected people and AIDS patients is different from healthy group, the heat ranks of the heart and lung are the lowest in healthy group, and liver and spleen set in the second place, kidney and life-gate are the highest in The Five Zang-Organs'heat ranks. In contrast, HIV/AIDS shows a inversion heat sequence in The Five Zang-Organs'heat ranks.3.2.3The Six Fu-Organs Three groups showed no significant relationship in The Six Fu-Organs'heat ranks,while. the difference is the heat ranks of The Six Fu-Organs of HIV/AIDS are totally lower than the healthy group.The results of Comparison of heat sequence within three group show us that: HIV/AIDS shows a inversion heat sequence in Triple energizer and Zang Fu.Organs, this is consistent with Transmission and clinical characteristics of AIDS, HIV/AIDS has a long history of selling blood, Sexual promiscuity and Intravenous drug, so it can directly damage qi and blood, qi and yin, essence and blood, which can induce asthenia of middle and lower energizer, injury of righteousness and kinds of Opportunistic infections. Heat ranks of The Six Fu-Organs of HIV/AIDS are totally lower than the healthy group showing that there is a serious metabolic disorder of HIV/AIDS group in digestion, absorption and excretion of foods and waters.4 ConclusionInfrared imaging technology have a responsive and precisive advantages, it can display temperature distribution timely, No matter continuous dynamic observation or different time temperature data can be analyzed; There is no radiation or exposure to the human body, and without any side effects on the examiner, Infrared heat map reflects the body's energy metabolism and basal metabolism changes, so it can better reflect the physiological and pathological changes of the body, According to the results of this study, the expression of infrared imaging technology close to the heat and cold, and also as the status of righteousness rise and fall of human body, It providing a comprehensive, systematic, and dynamic control instruments to measuring the phasic changes, trends and outcomes of human body for TCM Study,It has a wide applications in future Study of TCM.5 DiscussionIn this study, normal control group are mostly at the age of 18 to 24 years old, and mostly are male, which is different from testing group, In order to balance three groups, we adopted the statistical method of analysis of covariance, In future study, we will try to meet the age balance between groups, and we will gain more objective conclusions, if we compare by layer ages. In addition, we gain a general conclusion of syndrome differentiation of AIDS, that is cold and heat, asthenia and sthenia, The reason why we fail to gaining the distinctive Infrared caloric value of definite syndrome differentiation is relating to limited sample size and no unified diagnostic criteria of syndrome differentiation. This problem will be solvesd with sample size increasing and study of syndrome differentiation of AIDS deepening.