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Explore The Aids Treating Ideas, Based On The "treatise On The Diagnosis And Treatment Of Cold And Heat Mixed Card

Posted on:2011-07-12Degree:DoctorType:Dissertation
Country:ChinaCandidate:W Z ChengFull Text:PDF
GTID:1114360305472630Subject:TCM clinical basis
Abstract/Summary:PDF Full Text Request
AIDS, with full name of Acquired Immunodeficiency Syndrome, is a kind of infectious disease caused by the Human Immunodeficiency Virus-HIV. From the period of early 1980s, when HIV/AIDS was discovered, until the present-nearly 28 years-it ha killed thousands of people. And this causes great troubles in social and economic development. So it is called a "Supercancer " or a "Plague of the Century"For many reasons, up to now we haven't clearly categorized the syndrome, or the pathogenesis and evolution of AIDS. This has a direct and harmful influence on treatments, according to the differentiation of the syndrome, and evaluation of the effect of different therapies. So it is necessary for us to study HIV/AIDS syndrome from the perspective of traditional Chinese medicine(TCM). To collect the symptom characteristics and syndrome features by the way of clinic epidemiology while guided by the chief concept of TCM--wholism and treatment according to syndrome differentiation, evidence based medicine as well as statistic etc in order to identify syndrome type, and to discover the pathogenesis evolution law of HIV/AIDS, which will provide foundation for TCM treatment according to the syndrome and other related research. It will also improve the therapeutic Effect of HIV/AIDS by the way of TCM.Concluding from the retrieval documents/articles and the study of Clinical Epidemiological, the clinic manifestation and pathogenesis of HIV/AIDS is mainly same with the cold-heat complicated syndrome described in "ShangHanLun". So draw lessons from the trgeatment according to cold-heat complicated syndrome described in the "ShangHanLun", it will elevate the level of HIV/AIDS infection.ObjectiveTo explore the causes, syndrome characteristic, pathogenesis features, formulas of prescription and the function of prescription drugs of cold-heat complicated syndrome described in the "ShangHanLun"To explore the pathogenesis and syndromes of HIV/AIDS by means of a clinical epidemiological survey, with a large sample and clinic manifestation.To discuss the TCM treatment according to syndrome of HIV/AIDS from the view of formulas of prescription of cold-heat complicated syndrome.MethodsTo probe into the causes, syndrome characteristic, pathogenesis features, the formulas of prescription and the function of prescription drugs of cold-heat complicated syndrome described in the "Treatise on Exogenous Febrile Disease" by the way of study the retrieval documents/articles.HIV/AIDS infection and non-HIV/AIDS infection were selected randomly by Multistage-stratified-cluster sampling method from Oct.2005 in xx province. To gather the details of HIV/AIDS infection and the information which acquired through the four diagnostic methods as well as the final syndromes were recorded into the database which was established by Epidata3.01 software. Then do statistic data processing and analysis by software of SPSS 13.0, Lisre18.51.AdoptX2 inspection to deducing a statistic conclusion, and use SEM (structure equation model) in the research to explore the relationship between TCM symptom and syndrome of HIV/AIDS disease based on the Univariate analysis.Results1. Study results deduced from the analysis of cold-heat complicated syndrome in "ShangHanLun"Conclusion from the above mentioned cold-heat complicated syndrome described in "ShangHanLun" and the various practical case of cold-heat complicated syndrome:Features of cold-heat complicated syndrome were disordered of middle energizer of spleen and stomach.close realation of liver-gallbladder free coursing,long course of disease and deficiency of Zheng-qi. The main clinic manifestations are cold limbs, abdominalgia. stomachache, gastric stuffiness, anorexia, contracture of the umbilicus, chronic diarrhea and long-term of disorde diarrhea etc Syndromes. Stringy pulse coated yellow fur are the characters of tongue and pulse of cold-heat complicated syndrome. 2 Results of traditional chinese medicine(TCM) syndrome of HIV/AIDS patients2.1 Researcher had adopted of 1323 HIV/AIDS patients and 778 uninfected HIV control group. Results were as follows.The symptom frequency above 20% have 25 kinds in HIV/AIDS groups. Taste in the mouth,stomach duct pain,torpid intake,nausea and diarrhea were belong of spleen-stomach system.Cough.phlegm.dyspnea and throat-illness were belong of lung-system. Flusteredness-palpitations,chest pain and spirit disorder were belong of heart-system. Dizzyiness was belong of liver-system. spontaneous urination disorder was belong of kidney. lassitude of spirit, lack of strength, contracture of the body, aversion to cold, thirst, contracture of sleep, contracture of sweating, headache, generalized itching,lose hair,emaciated and enlargementlymph-knot were belong of the whole body symptom. There was difference between the two group on the 25 kinds of symptoms.2.2 Palse condition There were 175 kinds of palse condition in HIV/AIDS group.sunken_fine pulse,sunken pulse,sunken_fine weak pulse,string_like slipprey pulse,rapid_fine pulse, slipprey pulse, string_like fine pulse, sunken rapid_fine pulse, slipprey rapid pulse and sunken_fine vacuous pulse rounded off the top ten. There were 108 kinds of palse conditions in the controlling group. sunken_fine pulse, sunken pulse, regular, string_like fine pulse, slipprey pulse,string_like slipprey pulse, sunken_ weak pulse, string_like, sunken string_like pulse and fine pulse rounded off the top ten. There was difference between the two group on the sunken pulse, sunken_fine weak pulse, rapid_fine pulse, string_like fine pulse, slipprey rapid_fine and sunken_fine vacuous pulse.2.3Tongue colorThere were 26 kinds of tongue color tongue color in HIV/AIDS group. pale red tongue, blue tongue,pale tongue and red blue tongue rounded off the top five.There were 18 kinds of tongue color in the controlling group. pale red tongue, blue tongue and red blue tongue rounded off the top five. There was difference between the two group on the pale red tongue, red tongue and pale tongue.2.4 Form of the tongueThere were 24 kinds of form of the tongue in HIV/AIDS group. normal tongue, enlarged tongue, thin tongue, enlarged teeth-marked tongue and teeth-marked tongue rounded off the top five. There were 15 kinds of form of the tongue in the controlling group. normal tongue, enlarged tongue, thin tongue, teeth-marked tongue and enlarged teeth-marked tongue rounded off the top five. There was difference between the two group on normal tongue, enlarged tongue, enlarged teeth-marked tongue and teeth-marked tongue.2.5Motility of the tongueThere were 13 cases of limp wilting tongue and 5 cases of trembling tongue in HIV/AIDS group. There was not case in the controlling group. There was difference between the two group.2.6Sublingual collateral vesselsThere were 11 kinds of sublingual collateral vessels in HIV/AIDS group. Normal.thick.thin. blue purple and winding of sublingual collateral vessels rounded off the top five. There were 8 kinds of sublingual collateral vessels in the controlling group. There was difference between the two group on Normal.thick.thin, blue purple and winding of sublingual collateral vessels.2.7Texture of fur There were 42 kinds of texture of furin in HIV/AIDS group. Thin fur, thick slimy fur.thin slimy fur.thick fur.slimy fur and thin slipper moist fur rounded off the top six.There were 25 kinds of texture of fur in the controlling group, thin fur,thick slimy fur,thin slimy fur,thin slipper moist fur,slimy fur and thick fur rounded off the top six. There was difference between the two group on thin furthin fur,thick slimy fur, thick fur and thin slipper moist fur rounded off the top six. There was difference between the two group on Thin fur, thick slimy fur, thick fur and thin slipper moist fur.2.8 Fur colorThere were 11 kinds of fur color in HIV/AIDS group. white fur color, yellow fur color and white-yellow fur color rounded off the top three. There were 9 kinds of fur color in the controlling group. white fur color, yellow fur color and white-yellow fur color rounded off the top three. There was difference between the two group on white fur color, yellow fur color and white-yellow fur color.2.9 SyndromeThere were 123 kinds of syndromes in HIV/AIDS group. syndrome of internal obstruction of dampness-heat and spleen deficiency pattern, syndrome of internal obstruction of dampness-heat and spleen-lung deficiency pattern, syndrome of internal obstruction of dampness-heat and syndrome of dual deficiency of qi and yin, syndrome of internal obstruction of dampness-heat, spleen deficiency pattern, dampness-heat blocking the lung,syndrome of retained dampness-heat toxin and spleen deficiency pattern, syndrome of retained dampness-heat toxin and spleen-lung deficiency pattern, syndrome of internal obstruction of dampness-heat and syndrome of dual deficiency of qi and blood and Liver qi depression pattern and spleen deficiency pattern rounded off the top ten.There were 69 kinds of syndromes in the controlling group. Normal,spleen deficiency pattern,syndrome of internal obstruction of dampness-heat, syndrome of internal obstruction of dampness-heat and spleen deficiency pattern, spleen-lung deficiency pattern, Liver qi depression pattern, Liver qi depression pattern and spleen deficiency pattern, syndrome of dual deficiency of qi and yin rounded off the top eight. There was difference between the two group on syndrome of internal obstruction of dampness-heat and spleen deficiency pattern,syndrome of internal obstruction of dampness-heat and spleen-lung deficiency pattern. syndrome of internal obstruction of dampness-heat and syndrome of dual deficiency of qi and yin.spleen deficiency pattern, syndrome of retained dampness-heat toxin and spleen-lung deficiency pattern, syndrome of internal obstruction of dampness-heat and syndrome of dual deficiency of qi and blood and normal. 2.10 Syndrome and Structural Equation Modeling. SEMConclusionsFrom this Investigation and results of studies in the literature, the two features of the incidence of AIDS patients are exogenous and internal injuries, with long course, the variable condition, serious disease situation, the symptoms involve internal organs. AIDS is neither a simple V temperature disease, or purely internal injury consumptive, Zhengjia, evil nuclear, but a virtual cult love is false and true cold and heat mixed complex lesions. Mechanism of disease was unique on AIDS patients.Comprehensive AIDS clinical symptoms and tongue and pulse performance, AIDS stasis present mixed cold and heat, the key is hot and humid, additionally,spleen is weak, the long time of syndrome of internal obstruction of dampness-heat damage a healthy atmosphere, accompanied yin and yang loss of body fluid, qi and blood. Deficiency syndrome mainly present insufficient Yang gas of spleen and lung, involving the liver, kidney, heart, most of excess evil is wet and dirty, toxic heat, blood stasis. AIDS, often appearing mixture of cold and heat, can be created by using Xin Kai Ku Jiang method of Medical Saint Zhongjing, combined with AIDS pathogenic factors and characteristics of their own, different organs where the evil really different, of cutting and giving of treatment.The survey is based on a patient with AIDS, so the resulting symptoms grouping, syndrome classification, and pathogenesis have localized features. Whether Characteristics of the pathogenesis of AIDS equal with the rest, and the resulting AIDS TCM structural equation model is able to withstand the rest of AIDS TCM testing of data and the proposed treatment ways, which are needed to be studied in the future.
Keywords/Search Tags:Shang Han lun, cold and heat mixed complex lesions, acquired immunodeficiency syndrome, tongue manifestation, syndrom, Structural Equation Modelin
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