Study Of Traditional Chinese Medicine Safety Monitoring

Objective:Understanding drug safety monitoring system at home and abroad. Explore the new method of Chinese medicine safety monitoring evaluation. On the basis of guaranteeing the purpose of clinical drug safety and rationality on human, explore the development direction of database safety monitoring, to make it serve better for Chinese medicine safety monitoring. Carry out hospital centralized monitoring and analyze the characteristics and the law of the method of hospital centralized monitoring by clinical research.Methods:1. Analyze retrospectively status quo about Chinese medicine safety monitoring, retrieve domestic and foreign literature. Clear the diversity of drug monitoring methods at home and abroad and choose the most suitable traditional Chinese medicine safety monitoring method witch are database safety monitoring and hospital clinical centralized monitoring for China's characteristic.2. Design and establish perfect traditional Chinese medicine database. According to actual situation, use report data of adverse reaction on existing drug fully to establish database system witch has the function of query, search, storage, regulation and statistical analysis with Chinese medicine characteristic.3. Select different levels of hospitals and specify Shen Mai injection to execute clinical analysis and study of Chinese medicine safety in Sichuan. Adopt the detailed recording method of the use of drug-related, witch is mainly for centralized monitoring of drug source, calculate the rate of the drug corresponding adverse reaction and analyze the reason why it occurs, summarizes and evaluate the drug safety and rationality.Result:Database Construction has begun to take shape after about a year and a half of process of development and establishment. This database has fast data retrieval functions for traditional Chinese medicine manual and case reports and function of security intelligence analysis witch reaches the expected results. The main clinical problem of hospital centralized monitoring study for Shen Mai injection is that no symptomatic drug, drug beyond the specification indications, drug beyond the specification concentration, intravenous drug use dripping speed over drug normally speed, drug combined with over much, especially the case of being coupled with medicine injection.Conclusion:Establishment of tcmi adverse reactions database can help to store and analyze medical record information, perfect drug safety monitoring system, meet the users'need of study, communication, information query. Its functional design are relatively complete with a Chinese traditional medicine features, it promotes Chinese traditional medicine informationization, modernization and internationalization development. However, the intelligence analysis function is to be improved because of limited capability, this database need to make this effort.Centralized monitoring method not only can offer reference for prevention and treatment on problem about clinical Chinese medicine safety, but also the cases material collected are very detailed, accurate, and real.It can help to usesummarize the rules of tcmi adverse reaction.But it has certain limitation because of the time and the hospital selected.