Modern Chinese Literature Review Of Constipation

The exact mechanisms of constipation are not yet clear, relevant studies may be related to multiple factors. The occurrence now considered and colorectal motility disorder, pelvic floor dysfunction, psychosocial factors and abnormalities of gastrointestinal regulatory peptides related. Patients with constipation will affect appetite and intestinal absorption of nutrients, but also induce or aggravate cancer, cardiovascular and cerebrovascular disease an important factor. With the acceleration of the pace of social, dietary changes in the structure and functionof the gradual increase in the incidence of constipation. According to foreign sources, however, the incidence of chronic constipation, young as 3%,8% for the middle-aged, the elderly was 20%. According to epidemiological survey of chronic functional constipation of the incidence rate of 6.07%. Although functional constipation benign disease, but it is not only seriously affect people's quality of life, the treatment rate increased gradually. Treatment of the disease in many ways, Western medicine for this disease with symptomatic treatment, but treatment is not satisfactory, and adverse reactions are more prone to dependency, and may cause damage to nerve endings and increase intestinal symptoms of constipation. By understanding the causes of modern Chinese medicine, diagnosis and treatment, developed a variety of treatment and prescriptions, has certain characteristics and advantages, but the lack of standardization.ObjectiveClinical medicine for the treatment of constipation evidence-based medicine and programs of study based on the preliminary draw of the recommended medical treatment of constipation medication and treatment. MethodsThis study from the perspective of evidence-based medicine, through standardized, rigorous, authoritative search strategy to retrieve the past 5 years has published on TCM Treatment of constipation modern literature. Establish the authority of the modern TCM Treatment of constipation literature database for future scientific research and clinical disease based on literature research. Through the past 5 years, modern literature, constipation, constipation symptoms in Chinese medicine for principal component analysis, factor analysis and cluster analysis, the initial draw TCM symptoms of constipation and dialectical law of the distribution. Standardization of syndrome for the disease syndrome characterized system and the establishment of a research idea for the future provide the basis for clinical medicine to treat constipation. Method of using systematic reviews of clinical research and comprehensive understanding of the applications of methodology, problems, objective assessment of the overall level of quality of research and scientific evaluation of the clinical medicine research in the treatment of constipation, the efficacy and safety outcomes, and to seek medical treatment in the Better programs of this disease.ResultThe 4245 cases of 57 articles of in the literature in patients with constipation and information collection. Acquisition was Syndromes result, 17 kinds of symptoms 62,88 taste of Chinese medicine. Principal component analysis confirmed that these symptoms there is a certain correlation between, groups divided by cluster analysis and clinical description of the actual sum of the main symptoms of common syndromes and Chinese medicine drug use. Through this study, the preliminary draw the following conclusions can be:①Syndrome patients with constipation can be divided into hot secret card (heat syndrome), qi deficiency, qi secret card, blood deficiency, yin deficiency, Yang Deficiency;②The main symptoms to constipation, dry stool, stool frequency decreased defecation extended up to see, the main disease, summary of tongue and pulse, pale tongue with thin white fur, thready and weak pulse is the most common; By principal component analysis and cluster analysis will be combined with clinical symptoms grouped into six groups, namely, six major syndromes;③The use of traditional Chinese medicine to hemp seed, angelica, peony root is most prevalent, while the principal component analysis and cluster analysis, combined with clinical expertise to judge, and the combination of frequency analysis results can be classified into six major traditional Chinese medicine syndromes of the common Chinese. These results and the current in the medical textbook basically.However, the literature of Chinese medicine treatment of constipation of the following deficiencies:①nsufficient RCT articles;②Positive result is too high;③Type of drug used in the control group too, that non-specific drugs as controls, and a variety of methods of treatment, evaluation of efficacy;④Many studies relate only to effects, while ignoring the side effects;⑤Most of the recent focus on efficacy, not enough attention on the long-term efficacy.ConclusionIn the retrieval process, retrieval staff should have a clear idea of rigorous development of each step of the retrieval process, close by the logic of a good link, adjust according to retrieve the search strategy to enhance the full rate review. In recent years, scholars of the efficacy of TCM treatment of constipation was more research and have achieved some results, but lower quality of clinical research, the lack of convincing conclusions can not be clinical evidence to guide treatment Therefore, Chinese medicine treatment is not yet reached the standard of treatment of constipation. Clinical studies in the future, we need to use evidence-based medicine, clinical epidemiology and medical statistics rigorous design methods, measurement and evaluation, to obtain scientific conclusions, drawn Chinese medicine treatment of constipation and medication administration is the rule of law of evidence, Summarized the treatment of Chinese medicine treatment of constipation standards and programs to guide clinical practice, improve the efficacy.