Microencapsulation Of The Total Buckwheat Flavonoids And The Microencapsulation Adjustion On Blood Glucose

Flavonoids is distributes a broadest kind of ingredient in the vegetable kingdom,they often combine to form the glucoside form existence by the free state or with the sugar.The tartary buckwheat seed contains the flavonOids class compound mainly has:rutin,quercetin,Shah Naifen kaempferol,kaempferol-3-rutinoside,quercet in-3-rutinoside-7-galactoside,Mongolian oak skin element-3-pair of mouse Li Tanggan,Mongolian oak skin element-3-mouse Li Tangshuang glucose glucoside and so on.The total tartary buckwheat flavonoids has the oxidation resistance,the elimination free radical; Immunity adjustment;Adjustment cardiovascular system's function;Elimination toxic metabolite;Influence Cell multiplication;Protects the liver;Improvement memory,prevention senile dementia sickness;Anticancer treatment,against cancer function and so on.This research take tartary buckwheat as main material,uses the ethyl alcohol backflow law to the different extraction temperature,the extraction time,the ethyl alcohol density,the material granularity,the material fluid compared to conduct the research to obtain the optimum extraction condition.Uses the pocket polymeric adsorbent separation to purify the total tartary buckwheat flavonoids the craft,take the resin to grass cutter's adsorption rate,the desorption rate as the evaluating indicator,discussed has affected the total tartary buckwheat flavonoids separation purification several primary factors.Uses the spray drying technology,take the Arabic gum,Beta - the ring-like dextrin,the gelatin and so on as the wall material,carries on the microcapsule to the total tartary buckwheat flavonoids and conducts the research to the microcapsule product btoodglucose adjustment function.The results indicated:1,Through to withdraws the condition research to obtain the optimum extraction condition:When extraction temperature 70℃,time 4h,ethyl alcohol density 80%,granularity 60 item of materials,fluid compared to 1:25,the total tartary buckwheat flavonoids raises the extraction rate to be possible thickly to reach 7.831%.2,The D16 National Congress of the Communist Party of China hole resin's purification optimum condition is:On column condition:On type density 2.0 mg/ml,on type fluid pH value 6.5,on type fluid temperature 40℃.Elution requirement:Ethyl alcohol density 70%,eluent amount used 300mL.The separation extraction purity's determination result is 38.76%.3,The total buckwheat flavonoids microcapsule best wall material combination is:Arabic gum:Beta-the ring-like dextrin is 1:1,the gelatin content is 1%,the emulsifier single glyceride content is 0.3%;The core material and the wall material ratio is 0.1 g/g;Spray drying technological conditions:Expects the liquid solid shape density to control in 25%,enters the wind temperature to determine that is 180℃,the isotropic pressure is 30 MP,the feeding current capacity is 8mL/min.The product microcapsule rate and the microcapsule rate may reach above 90%.4,Total buckwheat flavonoids microcapsulate product target merit rating result:The moisture content is 2.38%,the density is 0.2876 g/cm3,the solubility be bigger than 90%grayish white,slightly,the product to brings the decadent powder,microcapsulation size dimensi on approximately between 5～25μm.5,The total buckwheat flavonoids microcapsulation to the normal big mouse body weight,empty stomach bloodglucose is not remarkable affects,the alloxan results hyperglycemia big mouse's body weight is not as well as the normal big mouse,has the remarkable influence to the alloxan,results hyperglycemia big mouse's bloodglucose as well as the alloxan,result hyperglycemia big mouse sugar tolerance.