Study On Relationship Between Inorganic Elements And Quality Of Cortex Moutan

Cortex Moutan is a commonly used Chinese medicinal material, Fengdan Peony (Paeonia ostii Andr.) from Fenghuangshan of Tongling, in Anhui province, is known as genuine medicinal materials because of excellent quality and curative effect. Fengdan Peony is transplanted in Bozhou of Anhui province, Heze of Shandong province, Dianjiang of Chongqing, and Shaoyang of Hunan province. Drug quality of Cortex Moutan from different regions are different. At present, the quality of Cortex Moutan is mainly evaluated by the content of paenol and such organic components, and meanwhile, more and more research shows that, inorganic elements have pharmacological effect on human, inorganic elements also have influence on the organic components. Studying on drug quality from the view of inorganic elements has become a research hotspot. Currently, some accomplishments have been made on the relationship between inorganic elements and drug quality, but there's no study on Cortex Moutan. The experiments were conducted to find the characteristics of inorganic elements of Cortex Moutan from Fenghuangshan of Tongling city and the relationship between inorganic elements and drug quality. Three kinds of inorganic elements selected according above results are used on Fengdan as trace fertilizer to aim at improving drug quality of Cortex Moutan. Technology support for establishment of Cortex Moutan quality standard and GAP will be gained through this research.The contents of twenty-two kinds of inorganic elements in the same germplasm of Cortex Moutan crude drugs and soils from different regions were determined by ICP-AES, and the obtained data were analyzed. The results showed that the contents of Cd, Cu, Mn, Ni, Pb, Ti, and Zn were higher in the geo-authentic Cortex Moutan, and they were found to be related with each other. So these seven kinds of inorganic elements were treated as characteristic elements of high quality Cortex Moutan. Positive correlation was observed between the contents of Al, B, Ca, Cu, K, Mg, Mn, Pb, Ti, and Zn in Cortex Moutan and soil, and negative correlation was observed between the contents of Co and Ni in Cortex Moutan and soil.Length, coarseness, phloem/xylem, content of paeonol, content of polysaccharides of Cortex Moutan from five different regions were determined and compared, the results showed that there was no significant difference on their appearance, but there was significant difference on the content of paeonol and polysaccharides. Correlation analysis between inorganic elements and organic components showed that Cd, Cu, Mn, Ni, Pb, Ti, and Zn were positively related with paeonol and polysaccharides respectively. Therefore, these seven kinds of inorganic elements are important reason of high quality of Cortex Moutan in Tongling.Three kinds of inorganic elements selected according above results were used on Fengdan as trace fertilizer. Foliage spray and root watering were taken on 3-year-old Fengdan in Heze of Shandong province. The drying rate, root activity, content of soluble protein, PAL activity, content of soluble sugar, starch, Length, coarseness, phloem/xylem, content of paeonol, polysaccharides, and inorganic elements were determined. The results showed that drying rate, content of paeonol and polysaccharides were increased by both applying methods of three kinds of trace fertilizer, and root activity was not influenced. The content of soluble protein, soluble sugar, starch and PAL activity were increased in certain degree. The contents of Cu, Mn, and Zn in Cortex Moutan were enhanced by both applying methods of three kinds of trace fertilizer. By the treatment of foliage spray, Cu, Zn, and Cd; Mn and Ni; Cu and Pb; Cu and Zn; Ti and Cu, Mn, Zn exhibited synergistic relationship. By the treatment of root watering, Zn and Ni; Mn and Pb; Ti and Cu, Mn, Zn exhibited synergistic relationship.