A Systematic Review Of Traditional Chinese Herbs For The Treatment Of Chronic Pelvic Inflammatory Disease

[Objective]To evaluate the effectiveness and safety of treatment chronic pelvic inflammatory disease.[Methods]To set up an evaluation table of the clinical research articles about treating chronic pelvic inflammatory disease with tcm after collecting rct and half-rct articles from both domestic and abroad data base from 1994 to 2007,and to do meta analysis with software of Review Manager(RevMan4.2) on the basis of statistic analysis in four aspects,that are general condition of the articles,criteria of diagnosis,inclusion and exclusion,criteria of effect judgement and research design.Sensitivity and heterogeneity were analyzed and tested;funnel-plot analysis was used to identify the publication bias.The method logical quality of trials was assessed by the Jadad-scale plus allocation concealment.[Result]1,Quality evaluation:Four trials are RCT and seven trials are CCT.None of the trials mentioned the concealer of distribution and just one document adopt single blind.None of them mentioned the number of patients who cannot be related or droped out during the trial and adopt intention-to-treat.All the included trials were of inferior methodology quality.2,The results of Meta-analysis suggest that herbs are better than antibiotics in treating the chronic pelvic inflammatory disease(P＜0.001) and that tcm has effective in clinic for chronic pelvic inflammatory disease in alleviation the pain of low abdomen and lumboseral pain and leukorrhgia and tenderness of uterus and succus in pelvic and incrassation of accessories,their odds ratio and 95%CI were[OR 0.26,95%CI(0.15,0.45)][OR0.29,95%CI(0.16,0.50)][OR0.41,95%CI(0.23,0.73)][OR0 .20,95%CI(0.11,0.39)][OR0.35,95%CI(0.13,0.97)][OR0.18,95%CI(0.10,0.32)].In improving low fever and lower abdominal mass,tcm as well as antibiotics(P＞0.05). 1 document observe the hemodynamics.3 trials report the recrudescence.4 studies report the adverse effect.[Conclusion]Chinese medicine has certain effects and safety in treating chronic pelvic inflammatory disease,and better than west medicine.At present,the Systematic Review does not suit to evaluate the effectiveness and safety of treatment chronic pelvic inflammatory disease with traditional Chinese herbs due to the low quality of the trials.