A Paired Case-control Study Of Selective Attention Function And Related Factors For Patients With Transient Ischemic Attack

Objective:With the redefining of transient ischemic attack, it appears importance to hold meanings of the nerval deficit entirely and exactly.At present,most researchers agreed upon those patients with transient ischemic attack have cognitive impairment.There are a lot of studies for memory function and executing function patients with transient ischemic attack,but few for attention function.For exploring situations of selective attention function and facilitating whole rehabilitation,we examine the selective attention function and its related factors of patients with transient ischemic attack.Methods:71 transient ischemic attack patients were selected in patient group and they were paired with another 91 normal persons as the control group against age and gender. All cases were assessed with Stroop color-word test,Mini Mental Status Examination,Self-rating Depression Scale, Self-rating Anxiety Scale,Pittsburqh Sleep Quality Index scale, selective attention function and self-designed information scale for demology,physical examination,blood assay.The selective attention functions and other indexes in study group were compared before and after 4 weeks. Results:The selective attention functions in study group were significantly worse than those in control group in postponing of action time,decrease of the accuracy and declining of restraining ability.The medications could improve those functions in a way.1.There were more persons with cigarette history and hypertension family history in study group than those in control group(P＜0.05 or 0.01).There were differences in family's earning between two groups(P＜0.05).The levels of Systolic Pressure and Hcy in study group were higher significantly (P＜0.05 or 0.01),HDL lower significantly than those in control group(P＜0.05).The scores of SAS,PSQI,Sleep Latency,Sleep Duration and Sleep Disturbance were higher significantly in study group than those in control group.In study group,action time and accuracy of Stroop color-word test,which were central indexes of selective attention function,were worse significantly than those in control group.2.The factors,including age,education time,smoking history,diabetes family history,MMSE,Hcy level,SAS,PSQI, Sleep Quality and Sleep Disturbance,were found to be connected with actions' time and accuracy,Stroop interference effect through single-factor analysis in TIA group.3.Systolic Pressure,Hcy,SAS were related to Stroop Interference Effect Time,Hcy,MMSE,PSQI and Sleep Disturbance were the effect factors for Time Per-Correct Answer of Card C through multiple lines analysis.4.With the compare between before and after treatment in patients,it was found that action time and accuracy were improved by medications.By Logistic multiple analysis,More times attacks,Systolic Pressure,Hcy,SAS,PSQI,Sleep Quality and Sleep Disturbance were the factors which caused the results' variety of Stroop color-word test.Conclusion 1.Transient ischemic attack patients have the selective attention deficits.2.The factors effecting selective attention function are multiple.3.The patients' selective attention function is plastic and medication could be helpful to some extent.4.With decreasing of Systolic Pressure and blood Hcy level, anxiety lightening and sleep improving,patients' selective attention would be better.5.Attaching importance to selective attention function of patients with transient ischemic attack will be benefited for diagnosis,therapy and rehabilitation in the round.