Objective To study the effect of continuous blood purification (CBP) on severe acute pancreatitis (SAP)Methods According to the diagnostic criteria, inclusion criteria and exclusion criteria , 72 cases of SAP with not less than 15 of APACHEII were divided into group with the treatment of imtegrated traditional Chinese and western medicine (ITCWM) and group B with the treatment of ITCWM and continuous blood purification.Further delamination,the cases of cure and improved were divided into group C(treatment with CBP) and group D(treatment without CBP). The scores of APACHEII and ranson,CT Severe Index,duration of physio and biochemical indicator,etiopathogenisis,course of disease and curative effect were analyzed contrastly.Results: In age,course of disease of out-hospital and the severity of pathogenetic condition,there are no significant difference between the two groups(all P>0.05).There have statistical significance between group A and group B .OR is 2.91.In group A , scores of APACHE II in the third day,the time of recovery of renal function and ARDS, blood of pH are more serious than those in group B(P<0.05).In group C,the duration of hospital,scores of APACHE II in the third day, hypocalcemia,enteroparalysis,blood of pH and serum of LDH,the time of recovery of renal function, are more serious than those in group D. (P<0.05)Conclusions: CBP could improve the prognosis,shorten duration of hospital,quickly stable internal environment,improve renal function,alleviate ARDS,promote the recovery of enteroparalysis and lighten systemic inflammation. |