| Root canal therapy is the main method of pulpitis and periapical periodontitis, and also is an important part of the endodontics. Modern root canal therapy is composed of 3 steps: root canal preparation , root canal disinfection , root canal filling. Which are successive process , that have inter connections and compensate each other. That is to say that when root canal preparing and root canal disinfection are better, even if the root canal filling are little bad , which also can therapy the pulpitis and periapical periodontitis. Otherwise also can get a better result. But what we need to pay attention to is that we will do each step carefully, just when we meet the difficult of root canal anatomy or the technique, that we can depend on the other steps. If we don't regard to the thoroughly cleaning up of the canal , also don't pay attention to the rigorous filling of root canal, the root canal therapy doom to defeat. So every steps of root canal therapy are highly regarded by the clinicians, and the root canal disinfection become one of the research focuses, especially in recently years researchers gradually regard that formo-cresol which is used most frequently in the root canal disinfection perhaps can make hurt to the tissues of the peripheral root , even lead to cancer or mutation, so searching for new effective and less adverse effects medicines of root canal dressing become the focus of clinicians and researchers. As root canal dressing medicine , calcium hydroxide's(Ca(OH)2) curative effect has been testified by the lab and clinic, now it has broadly used in the clinic.ObjectiveThe purpose of this study is to compare the curative effect of different medicines mixed with calcium hydroxide as root canal disinfection medicines, and discussing the disinfection ability of different medicine complex.MethodsRandomly choosing 290 patients of acute and chronic pulpitis, pulp necrosis, acute and chronic periapical periodontitis, include 155 males and 135 females , each person was choose 1 tooth, so there are 290 teeth. The patients' age vary from 19 to 61, average is 39. Tooth distribution: 54 upper anterial teeth, 42 lower anterial teeth, 55 upper premolars, 44 lower premolars, 47 upper molars, 48 lower molars. The type of the disease(clinic syndrome , pulp vitality testing, x-ray diagnoses): 103 acute and chronic pulpitis, 89 pulp necrosis, 108 acute and chronic periapical periodontitis. Including criteria: every patients only involved 1 tooth, unambiguous diagnoses, not taking root canal therapy before, can filing to the root apical(no pulp calcification), no severe disease, no severe infection, not using antibiotics in last 1 week. The patients were randomly divided into formo-cresol solution group, camphor phenol(CP) group, calcium hydroxide group, calcium hydroxide and iodoform compound paste group, calcium hydroxide and metronidazole compound paste group, calcium hydroxide and dexamethasone compound paste group. Treated by the same dentist, first time: entrying into the pulp chamber through enamel with a fissure bur on the painless condition. Then open the pulp chamber, clean the root canal with barbed broach, wash the root canal with 3% H2O2 and 0.9%H2O. On the purpose of improving the comparability, every tooth whatever has acute symptom before therapy open the chamber just put a tampon in it for 1 week. And at the same time remove the occlusal hurt. Second tims: Root canal preparing. Cleaning and preparing the root canal with files, at the same time washing the canal with 3% H2O2 and 0.9%H2O. Then dry the canal. After that put FC or CP tampon in the chamber or CH+iodoform,CH +metronidazole, CH+ dexamethasone paste in the canal. If there are not IAE happening , letting the patients consult 1 week late. Otherwise consult as soon as the teeth ache. Third time: After no edodontic interappointment pain (IAE) happening, wash the canal with 3% H2O2 and 0.9%H2O, dry it and fill with gutta-percha and paste.Resultscalcium hydroxide group, calcium hydroxide and iodoform compound paste group, calcium hydroxide and metronidazole compound paste group, calcium hydroxide and dexamethasone compound paste group are better than the formo-cresol solution group and camphor phenol group in the IAE incidence, pain degree and curative effect(P<0.05). There are little different in the former groups(P>0.05). But the calcium hydroxide and iodoform compound paste group show better therapy effect in the periapical periodontitis.ConclusionDifferent root canal dressing medicine have different effect. The pastes containing calcium hydroxide have better effect than formo-cresol solution and CP. And there are same effect of the pastes containing CH. Only the CH and iodoform compound paste group show better therapy effect in the periapical periodontitis. |