Investigation And Confirm Atory Factor Analysis Methods In Patients With Cough Variant Asthma

cough variant asthma (CVA) is a kind of special asthma, chronic and stubborn cough is its only or main clinical symptom. And its main clinical symptom include:persistent cough or repeat cough over one month, mainly happen on night or wee hours, mostly irritative cough, aggravated after movement, without infection, ineffective cured by antibiotic, catabatic by bronchial dilatation drug, without wheeze in lung, mostly have personal or familial hypersensitivity, cough variant asthma were considered as supersensitive bronchitis or dormant asthma before, this disease was first reported by Gluser in 1972, and named it as cough variant asthma, cough variant asthma happens in each seasons of year, especially spring and winter, according to the research:28 percent of patient suffer from chronic hacking cough have air high reactivity(AHR).and 46 percent of patient with AHR were considered as cough variant asthma, and developed to typical asthma. The incidence of cough variant asthma is high in child, it was found that over 30 percent of hacking cough in child related to cough variant asthma. The age of having cough variant asthma is higher than having typical asthma in adult, about 13 percent of patient over aged 50, mostly of them are middle age women. CVAis a kind of special asthma, its cause and machansim is complicated, and it is hard to cure. Only 10 years recently, it begaun focused on and deeply researched by medical science field. CVA probabily related to infection, descendiblity, circumstance and lower immunity. CVA's mechanism is still not clear, in recent years, the medical science field come to conclusion that it related to tracheal inflammation, air high reactivity(AHR), immunity, nerve mechanism, cellular factors etc. The asthma group of association of Chinese medicine established《guideline of diagnosis and treatment for cough(drafted plan)》, the guideline reflects the latest research in domestic and international medical field to pathogeny, mechanism and diagnosis for CVA. Treatment aspect, once it was diagnosed as CVA in western medicine, then stop the applied antibiotic or virussafe medicine, avoid the allergic source at the same time. Insist long-term, keep on, normal, individuation treatment principle. The head chooses medicine are the bronchial dilatation drug and hormone, often unite the both two drug. But the side effect of long-term using both two drug is obvious, especially for child, and having the shortage of recur soon and less curative for long-term using, traditional Chinese medicine also have no the clear and definited diagnosis standard. So it is urgently for traditional Chinese medicine to deeply analyzed and research on the definition,diagnosis standard and treatment of CVA, then guide clinical, further develop the advantage that traditional Chinese medicine treat on this disease.Objective: To investigate the information acquired through the four diagnostic methods of traditional Chinese medicine in patients with cough variant asthma, and to classify the syndrome types.Methods: One hundred patients with cough variant asthma were randomly investigated. The information acquired through the four diagnostic methods was recorded, created the database by Epidata software and the database was established by EQS1.6 software, and then the datawere analyzed by confirmatory factor analysis (CFA).Results: After analyzing the data with 4 factors and 5 factors。we found that the results of CFA with 5 factors were in accordance with clinical practical experience.Conclusion: According to the results of CFA with 5 factors and with the standard regression coeficient 0.4 as primary and secondary critical points, the syndromes in patients with bronchial asthma can be classified into 5 types, which are syndromes of wind infracting lung, cold fluid retained in lung, lung and kidney qi-xu, lung and spleen qi-xu, lung yin deficiency.