Experimental Study On The Treatment Of Yi Tai Compounded Medication Cure Chronic Pancreatitis Of Spleen-Asthenia Syndrome

Chronic pancreatitis is a disease with the durative scathe of pancreatic texture function. It is caused by diversiform reasons. The primary clinical representation is the reiterative paroxysmal bellyache ,mara mus and the incretory or exocrine function scarcity, the fatty laxness, diabetes mellitus and so on. Traditional Chinese Medicine thinks chronic pancreatitis is in the range of bellyache, diarrhea, the syndrome of mass and abdominal mass,etc. In clinic, most of chronic pancreatitis patients suffer from the disease for a long time and their clinical representation is mainly the weakness of spleen and stomach. Improper diet and emotional maladjustment may lead to the illness's recrudescence and turning to complexity. Because of the pathomechanism of qi stagnation and blood stasis, the syndrome belongs to asthenia in the root and sthenia in the branch. Spleen has the consanguineous relation with digestive system. The abnormity that is the texture and function of digestive system is the most elementary diversification of spleen. The multitudinous modern studies about spleen-asthenia syndrome indicate that it has the consanguineous relation with pancreatic exocrine function. Whereas this, our problem group try to confirm the relation between chronic pancreatitis and Spleen-asthenia syndrome from Histology's and biochemistry's angle through the study of the rat model of which L-Arg leads to the spleen faint pancreatitis. And on the base of the model, we draw a conclusion to the curative action of "the spleen fitness capsule."The study consequence are followed. The rats injected L-Arg appeared to the typical reflect of the Spleen-asthenia syndrome, and the altering of pathologic morphology come to the diagnostic standard ofchronic pancreatitis. The modal edtablished successfully; thoughoptical mirror and electronic mirror, we observe the spleen's pathologic pattern and super-ting frane of chronic pancreatitis and prove that area's recovery and the descend of the fibrosis degree and the decrease of the apoptosis; The test of diastase findings even more confirmed the reliability of the means's curative action from the objective angle. Experimental findings indicate that there are the experimental value to cure chronic pancreatitis with "YI TAI Compounded Medication" which are produced according to "the treatment of invigorating spleen and promoting blood by regulating qi", thus the means inaugurates a new approach for the disease's remedy.