The Clinical And The Experimental Studies Of The Relationships Between Deficiency Of Kidney And Sensorineural Deafness | Posted on:2001-07-26 | Degree:Master | Type:Thesis | Country:China | Candidate:P Y Wang | Full Text:PDF | GTID:2144360002451103 | Subject:Medicine otorhinolaryngology | Abstract/Summary: | PDF Full Text Request | Sensorineural deafness (SND) which is a kind of commonly encountered and one of difficult otopathies , often leads to life-long hearing disability, whose basic clinical feature is that the hearing of air conduction and bone conduction reduces simultaneously , and whose pathological changes are in the hair cells of spiral orgon acoustic nerve and the hearing center. With regard to SND , there are no efficacious and generally accepted therapeutic tools up to now due to its complicated pathogenic mechanisms Modem medicine emphasizes the affectness of extrinsic factor in the study of SND , and lays particular emphasis on the ear of the outside causes of deafness to the sudy of physiology and pathology of hearing , and seldom researches how other systems or the internal environment of the body to influence the hearing . The holistic concept is an important idea of the traditional Chinese medicine (TCM) in preventing and treating diseases . According to the TCM抯 standpoint, though auditus is the main function of the ear , its origin lies in the kidney棓The kidney has the ears as its opening? The kidney is closely related to the ear This viewpoint has been proved by the modern medicine . Deficiency of kidney can lead to deafness. Clinical studies have primarily showed that half of the patients who belonged to deficiency of kidney had sensorineural hearing loss . Experimental studies have also observed that changes of cochlear bio-electricity happened in guinea pigs when they were in the state of Yang ?deficiency of kidney . Herbs of warming the kidney ?Yang can improve this situation . And so ,the TCM抯 treatment of reinforcing the kidney with good curative effects has been attached importance , which partly reflecting the relationships between the ear and the kidney. But there are many deficiencies in the studies of treating SND. For examples lacking objective standards of detection in lots of clinical reports ; no uniformal criterion of diagnosis and therapeutical effect ; seldom having duplicate tests ; hardly 4 thinking of relevant resource or state of illness with natural curative effects etc.There is very few the study about the characteristic of the animals?auditory changes and corresponding regularity of the inner ear抯 morphological changes when they are in the state of kidney ?yin - deficiency Then , what抯 the mechanisms of the herbs of invigorating kidney ?deficiency in treating SND ? What抯 the characteristic of auditory changes when animals are in the state of kidney ?deficiency (kidney 梱in ?deficiency)? And what抯 the mechanisms of which kidney - deficiency can results in SND. We try to discuss these questions from the clnical and experimental studies. The concrete methods as follow: 1. Clinical observations : We selected 43 patients(including 73 ears) who fited diagnostic and indusive criterias (male to female : 1 0.54 ; average coure 3.41 years ; mild deafness 16 ears , rate is 21.9% ; moderate deafness 17 ears ,rate is 23.3%; severe deafness 21 ears , rate is 28.8% ; extremely severe deafness 19 ears ,rate is 26%) to undertake auto ?control ,we adopted current domestic authoritive criterion of diagnosis and therapeutical effect to observe the curative effect of the method of invigorating the kidney for treating these patients . Combining together the experimental results , we initially discussed the mechanisms of QiQiaoZhiLong pills in treating SND. | Keywords/Search Tags: | DFNESS/trational, chinese medicine therapy, KIDNEY ASTHENIA/physiopathology, HEARING, DISEASE, MODELS, ANIMAL, GUINEA, PIGS | PDF Full Text Request | Related items |
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