Optimization And Application Of Highly Pathogenic Avian Influenza Immunization Programs

Highly pathogenic avian influenza, which is a spirits zoonosis, is caused by the Influenza virus type A, where H5, H7 subtypes are belong to strong strain of highly pathogenic, it is most harmful to the poultry industry. It is onset rapidly, spread quickly, high mortality, it is bring to poultry rations with significant loss. In this study, we discussed from drug-type strain, vaccine screening, immunization procedure, integrated control, this is the first time to started a comprehensive research from the source in the country, it will effectively prevent and control the occorrence and spread of bird flu, prompting the healthy development of aquaculture, protecting human health and safety.1.Using poultry influenza subtype H5 inactivated oil emulsion vaccine in Weike Biotechnology, Qingdao Yebio Biotechnology and Guangdong Dahuanong Animal Health Products Company, the first immunization effective are very good, and antibody titers come to peak value after 21d.According to effective of vaccine and physical truth, we choose vaccine in Qingdao Yebio Biotechnology.2.Maternal antibodies of chicken bird flu in three days is highest, followed by the growth of age with antibody titers decreased gradually, to 30 days of age antibodies disappeared. Ducklings bird flu maternal antibody on day 1 is the highest,3 to 5 days of antibody titers appears reaching plateau, then gradually decreased, and maternal antibodies have disappeared in 30 days.3.Screen out the immunity process that fits for preventing the bird flu in the city. The fowl is immunized for the first time when it's 10 days old, the second time when 40 days old to strengthen the immunity, he third time for laying hens and ducks t when 120 days old, and after that it is strengthened the immunity once every 4 months.4.Development of new immunization programs, promote the use of the city, the overall level of immune antibodies in 2004 was 45.1%,2005 was 48.9%,2006 was 56.7%,2007was 63.8%,2008 was 85.2%,2009 was 92.4%.After the 2008 promoting results of the project The whole city has greatly increased the level of immune antibodies, it reached the level of immune protection that Statistics whole antibody protection requirements more than 80%, In the city for three consecutive years of zero occurrence of highly pathogenic avian influenza provided a strong basis for protection.