| Object:Chronic atrophic gastritis(CAG) is a common disease in the digestive system.As a precancerous condition.it is significantearly to delay the occurrence of gastric carcinoma by early diagnosis and early treatment.Helicobacter pylori(Hp) infection is an important cause of CAG.It is a significant risk factor for gastric cancer.Eradication of Hp is the key to block the progress of CAG.Research shows that under the combined treatment of traditional Chinese and Western medicine can not only improve the eradication rate of Hp.but also can relieve the clinical symptoms.But as pathogenesis of CAG is comple and clinical syndrome has not been completely unified,it brings a lot of adverse for syndromes of this disease being standardize.Therefore,to study the pathogenesis and syndrome distribution rule analysis of chronic atrophic gastritis can better serve for the clinical curative effect and improve the clinical efficacy.The subjects:This paper consists of two parts:theoretical research and clinical research.The first part is theoretical research:summarizes the general situation of study on Hp infection and chronic atrophic gastritis at.The second part is the clinical research.observation of 195 patients with information.who were diagnosed chronic atrophic gastritis by gastroscopy and gastric mucosal histopathology.Entered the patients basic information.previous Hp infection history.clinical information and other data into the EpiData database.Import the data into SPSS17.0 and use non parametric test,correlation analysis.factor analysis and other statistical methods to study the relationship of Hp associated CAG on the syndromes of traditional Chinese medicine.syndrome element distribution characteristics and the correlation between Hp and pathological diagnosis.Mothods:(1)This study suggests that the prevalence of female and older is higher.Different gender and different age are differences in pathological diagnosis.but they are not linear correlation.Work pressure,smoking,drinking and dietary habits may be risk factors for the disease.(2)Study shows that the disease is common clinical symptoms of stomach.liver and systemic symptoms.(3)By factor analysis and determine the type of the syndrome,there is 8 types of CAG.They are similar the weakness of the spleen and stomach syndrome.similar syndrome of dampness heat of liver and stomach.similar syndrome of stomach yin deficiency.similar syndrome yang deficiency of spleen and stomach.similar syndrome of stomach collateral stasis of blood,similar syndrome of spleen deficiency and dampnes.similar syndrome of liver qi stagnation,similar syndrome of spleen stomach damp heat.The syndrome elements of disease location are mainly the spleen,stomach.liver.The syndrome elements of disease are mainly deficiency syndrome and excessive syndrome.The deficiency syndrome elements mainly include qi deficiency,yin deficiency,and also have yang deficiency.The excess syndrome elements are mainly qi stagnation,heat.wet,and also have blood stasis.Results:Through factor analysis of 195 cases of patients with clinical data and diagnostic information found that the syndrome elements of disease location are mainly the spleen.stomach and liver.The syndrome elements of disease are mainly deficiency syndrome and excessive syndrome.The deficiency syndrome elements mainly include qi deficiency.vin deficiency.and also have yang deficiency.The excess syndrome elements are mainly qi stagnation.heat.wet.and also have blood stasis.Patients with Hp positive and negative are both manifested as similar the weakness of the spleen and stomach syndrome and similar syndrome of liver qi stagnation.But patients in Hp positive patients are more manifested as similar syndrome of spleen stomach damp heat similar,syndrome of stomach collateral stasis of blood and more easy to damage the qi of spleen than patients in Hp negative patients.this may be related to Hp for damp heat evil and have strong pathogenicity. |
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