Investigating Toxicity Grading Of Toxic Traditional Chinese Medicine And Summaring Experience About Using Toxic Traditional Chinese Medicine Of Professor Peng Wannian

Objective:According to analysis the correlation about "syndrome-effect-poison" and "dose-effect-poison" of toxic traditional Chinese medicines and toxicity classification of traditional medicinal, putting forward new possibilities for toxic Chinese medicines modern toxicity grading opinions. Summarizing the experience in using traditional Chinese medicines of the tutor.Method:(1)In the school library retrieval system, through the general out of toxic Chinese medicine literature retrieval and advanced retrieval and materia medica books are summarized, after careful thorough reading. (2)83 toxic Chinese medicinal materials and crude drug of the Chinese pharmacopoeia (2015 edition), which entred to the Excel software, in order to 83 toxic Chinese medicinal materials and crude drug classification, si-qi, five flavours, belong to the summarized, such as correlation analysis on the properties and toxicity; (3)To mentor 818 prescription of tutor, recorded Excel spreadsheets, using SPSS15.0 software to toxic Chinese medicine prescription screening, frequency, etc of the TCM statistical analysis.Result:Listed by retrieving the ancient materia medica books, sum up the ancient materia medica books of toxic traditional Chinese medicines classified roughly divided into "exrermely poisonous drugs", "poison", "mild toxicity", Mainly according to each subject that clinical medication experience points. Along with the development of The times, the modern toxicity grading method is research methods of modern toxicology, the toxic effect of toxic traditional Chinese medicines on normal, although have the specific data of the traditional Chinese medicine toxicity, but didn’t and clinical medicine of traditional Chinese medicine, the combination of the lack of traditional Chinese medicine characteristics."Syndrome-effect-poison" and "dose-effect-poison" of toxic Chinese medicines are Based on syndrome differentiation, according to the patinet’s specific symptoms flexble drug using, and not constrained by rigid rule. When patients need medication or drug use, we due to time, place and people, compatibility to develop rigorous theory formulas, set a thief to catch it, achieve therapeutic effect.Traditional medicinal of toxic traditional Chinese medicine has certain relevance with species, the four properties, the five flavours and channel tropism. According to the China pharmacopoeia(2015 edition)the first part, we have statistrcal analysis that there is correlated with medicinal properties about species, the four properties, the five flavours and channel tropism of 83 Journal of Chinese Medicinal Materials and prepared herbal medicine in small pieces ready for decoction. From the species, most toxic drugs for plants, anmial and mineral are less toxic drugs. From the four properties, toxic Chinese medicinal materials and prepared herbal medicine in small pieces ready for decoction, more heat and cold, extremely poisonous drugs have heat, warm, cold, middle poisonous drugs have warm, cold, heat, mild poisonous drugs tend to materials and prepared herbal medicine in small pieces ready for decoction have sour and bitter. Extremely poisonous drugs tend to sour and bitter, middle poisonous drugs have sour, bitter and sweet, mild poisonous drugs tend to bitter, sour and acerbity. From channel tropism, Journal of Chinese Medicinal Materials and prepared herbal medicine in small pieces ready for decoction have two meridians with the liver and spleen, Extremely poisonous drugs tend to the liver and spleen, middle poisonous drugs tend to the liver, spleen and lung, mild poisonous drugs tend to liver, stomach, spleen and large intestine.So, in the toxic Chinese medicine toxicity grading, we can combine "Syndrome-effect-poison" and "dose-effect-poison", and traditional medicinal and modern toxicology research methods about specific indicators of toxicity clsssification together, it can yet be regarded as a new hierarchical likehood.Through to the tutor statistical analysis of clinical prescription and clinical basis for example, Summarizing the experiences of the teacher use of toxic traditional Chinese medicines. The tutor considers based dieases of patients when prescribing, saving the qi-of-stomach and the fluid, promoting blood circulation to remove blood stasis, at the same time, considing the new symptoms of patients, syndroming differentiation and treatment, using medicine clinically flexibly. In particular, first, using traditional chinese medicines in times, second, reasonable drug compatibility and proper dosage, third, rational to treat patients with "get inflamed" evaluation phenomenon after taking medicines.