Optic atrophy is one part of the neuro-ophthalmic diseases, Any injuries from the nerve fibers originate from retinal ganglion cells to visual pathway of the optic chiasm could lead to optic atrophy. Through traditional notion, it pointed that optic atrophy was the final result of serious damage to optic nerve, but, by modern research, it thought that optic atrophy is a pathological and morphological concept. Usually speaking, there were1to1.2million optic nerve fibers, whole atrophy nerve fibers were irreversible pathological change. However, Being pathological damaged or not damaged nerve fibers, once detected primary lesion and early treatment, or acceptting integrative medicine, then there will be the opportunity to restore or improve visual function, at least retain visual function. Therefore, the diagnosis and treatment of integrative to optic atrophy have also been concerned of more clinicians.This subject is under the guidance of the theory of traditional Chinese medicine organs and blood theory. Using prospective, randomized, double-blind, controlled study, it evaluated the efficacy of using Weishi prescription "Qingmang yi hao" to treat optic atrophy, aim to obtaining a high level of clinical evidence.The thesis consists of the literature review and clinical observation.The literature review includes two parts, optic atrophy and theoretical basis in TCM of optic atrophy. In the first part, it mainliy records the optic nerve anatomy and histology, the definition, classification, etiology, histopathology, clinical features, diagnosis and treatment of the optic atrophy. In the second part, it mainly review the medical name of disease, the etiology and pathogenesis, the dialectical type and the understanding of the Chinese ophthalmology.Clinical observation part:Objective:To evaluate the clinical efficacy of the Weishi prescription Qingmang yi hao " to treat optic atrophy.Method:from July2012to April2013,30cases with optic atrophy through different etiology which lead to liver deficiency type, and accepting the prospective, randomized, double-blind, controlled scudy methods, observing target were vision, visual evoked potential and change of vision.Results:There are no significant differences about the age and the basic vision, so they are comparable. The test group and the control group, visual evoked potential peak latencies changes were no significant difference in before and after treatment visual acuity, there were significant difference in visual field, The difference was significant in the two groups.Conclusion:It was efficacy to apply the Qingmang yi hao to treat the patients with optic atrophy which were the type of liver stagnation and blood deficiency. |