Research On Syndromes Distribution Law Of PMDD In Traditional Chinese Medicine

Objective1.In research of the distribution law of symptoms and syndromes ofPremenstrual Syndrome(severe,PMDD),summarized from Traditional ChineseMedicine literature in recent30years,we are aimed to provide references formaking scientific questionnaires.2. Discuss preliminarily the distribution rules of symptoms and syndromes ofPMDD in the view of Traditional Chinese Medicine, to find more references forthe clinical research.Methods the study is divided into three parts:1.Theoretical study:from the disease in ancient medical literatureresearch,modern medicine in the etiology and pathogenesis of thedisease,treatment methods,animal experiments,to the West Medicine on theepidemiology research,the pathogenesis and treatment progress in respect ofthe PMDD and PMS,the recent research on Chineses and Western Medicine wasdescribed systematically.2.Literature review: We analysed the correlative items in the literature ofPMDD and PMS symptoms in recent30years.3.Clinical epidemiology: Investigation of different groups,aged from18to45,750women, the patients with PMDD who were screened preliminarily began to complete the general circumstances and medical history enquiry,"PMDDsymptoms of TCM questionnaire","coating on the tongue and pulse conditionof PMDD questionnaire"and "PMDD syndrome questionnaire".Based on theanalysis of questionnaires,we discussed the distribution law of PMDD.Results:1.After abstracting,the common syndrome types of the disease were based onsyndrome of liver-qi stagnation, syndrome of liver-qi stagnation transforminginto fire, syndrome of liver stagnation and spleen deficiency, syndrome ofyin deficiency of liver and kidney, syndrome of yang deficiency of spleen andkidney, syndrome of qi stagnation and blood stasis.The disease locations werebased on liver and related to spleen,kidney and other apparatuses.Thepathological nature was mixture of asthenia and sthenia.The sthenic syndromewas mainly on syndrome of qi stagnation; the asthenic syndrome was mainly onsyndrome of qi deficiency.2.The diagnosis of PMDD was confirmed in44of750women (5.87%) who completedthe spot investigation,and age of onset was between31and45years old.3.Clinical epidemiology:based on the analysis of "PMDD symptoms of TCMquestionnaire", and "PMDD syndrome questionnaire",it was found that theprincipal syndrome type of PMDD were based on syndrome of liver depressionof the fire,syndrome of liver qi invasion; the secondary syndrome type of PMDDwere based on syndrome of yang deficiency of spleen and kidney, syndrome ofliver stagnation and spleen deficiency and syndrome of liver stagnation andblood stasis. The general symptoms were chiefly on irritable,dry throat,vexation and weakness in loin and knees.Conclusion:According to the results of literature review and clinical epidemiology,themain symptoms,syndrome types,etiology and pathogenesis of PMDD are tied upwith liver,which provides theoretical and clinical evidence for treatmentwith liver.