Correlation Analysis Between TCM Syndrome Types And Objective Indicators In Different Clinical Classifications Of Coronary Heart Diseas

Purpose:Through the analysis of coronary artery atherosclerotic heart disease(coronary atherosclerotic heart disease,CHD)three different clinical classification of TCM syndrome of distribution,further combined with clinical index,compare CHD three different clinical classification of clinical index between clinical index,mining contributes to coronary heart disease different clinical classification of TCM differentiation of objective index,for different CHD clinical classification of traditional Chinese medicine syndrome differentiation to provide clinical basis.Material and method:Through clinical epidemiological investigation and cross-sectional research method,295 patients who visited the Department of Cardiology,the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine and met the diagnostic criteria for coronary heart disease from January 2020 to January 2023 were investigated.According to the diagnostic criteria of western medicine,they were divided into three groups: stable angina,unstable angina and acute myocardial infarction,The researchers collect the information of TCM four diagnosis for TCM syndrome differentiation,under the guidance of two deputy chief Chinese medicine doctors or above.When the syndrome type is complicated and the results of two Chinese medicine doctors are different,the third deputy director or above Chinese medicine doctors will conduct the syndrome differentiation and judge again.The basic information,biochemical indicators,cardiac ultrasound results and contrast results of the included patients were collected,and NLR and Gensini scores were calculated.The data were used to analyze the correlation between TCM syndrome types and clinical indicators using SPSS24.0 statistical software.Results:1.A total of 295 CHD patients were included in this study,and the number of each syndrome type was ordered from more to less:According to the number of patients: qi deficiency and blood stasis syndrome,qi and blood stasis syndrome,heart and kidney Yin deficiency syndrome,qi and Yin deficiency syndrome,phlegm and blood stasis syndrome = heart and kidney Yang deficiency syndrome;the proportion of qi and blood stasis syndrome and blood stasis syndrome is more,while the rest of the syndrome is more,the proportion of women is significantly more than that of qi and blood stasis,with statistical difference(p <0.05);age was unrelated to syndrome distribution(p> 0.05).2.Among the three groups,stable angina group in 120 patients,90 patients in the unstable angina pectoris group,85 patients in the acute myocardial infarction group,The difference in the distribution of each classification was statistically significant(p <0.05),From more to less,Stability angina pectoris group: qi deficiency and blood stasis syndrome> phlegm and blood stasis mutual blockage syndrome> qi stagnation and blood stasis syndrome> qi and Yin deficiency syndrome> heart and kidney Yin deficiency syndrome> phlegm turbidity and closed obstruction syndrome> blood stasis obstruction syndrome = heart and kidney Yang deficiency syndrome;Unstable angina pectoris group: phlegm and blood stasis complex syndrome> qi deficiency and blood stasis syndrome> qi stagnation and blood stasis syndrome> qi and Yin deficiency syndrome> phlegm turbidity and closure obstruction syndrome = heart and kidney Yin deficiency syndrome> heart and kidney Yang deficiency syndrome> blood stasis and blood obstruction syndrome;Group of acute myocardial infarction: phlegm and blood stasis mutual blockage syndrome> qi deficiency and blood stasis syndrome> heart and kidney Yin deficiency syndrome> qi and Yin deficiency syndrome =phlegm turbidity and closed obstruction syndrome> qi stagnation and blood stasis syndrome>blood stasis obstruction syndrome> heart and kidney Yang deficiency syndrome.Among them,patients with qi stagnation and blood stasis in stable angina group than myocardial infarction(p <0.05).3.There was no statistical difference between the NLR and CPR levels in the three groups(p> 0.05).4.The levels of ApoA 1 and Lp(A)were significantly different among the three groups(p<0.05),ApoA 1 was significantly higher than blood stasis syndrome,and Lp(A)was significantly higher than blood deficiency syndrome and blood stasis syndrome(p<0.05),and there was no statistical difference between the remaining types(p> 0.05);but there was no statistical difference between ApoA 1 and Lp(a)levels in unstable angina group and acute myocardial infarction(p> 0.05).5.There was no statistical difference between the size,EF value and Gensini score of patients with coronary heart disease(p> 0.05).Conclusion:1.Patients with three different clinical types of coronary heart disease had the two types of qi deficiency and blood stasis syndrome and phlegm deficiency and blood stasis syndrome,while women accounted for a higher proportion of qi stagnation and blood stasis syndrome.2.The proportion of qi stagnation and blood stasis in stable angina patients is significantly more than that in patients with acute myocardial infarction.3.There is a correlation between ApoA 1,Lp(A)and TCM syndrome types in patients with stable angina;NLP,CRP,left ventricle size,EF value and Gensini score are difficult to be the reference indicators to guide the differentiation and classification of the disease.