| Objectives1.Construct mental resilience mini-program for patients with intermittent chemotherapy for breast cancer.2.Developed a small program of mental resilience for patients with intermittent breast cancer chemotherapy(1.0).3.Iterative development of mental resilience mini-program for breast cancer patients in intermittent chemotherapy(2.0).4.The psychological resilience mini program(2.0)was applied to verify its intervention effect on psychological resilience,anxiety and depression,social support,quality of life and self-efficacy of patients with intermittent breast cancer chemotherapy.Methods1.Based on the preliminary research results,literature review and group discussion,the small program of psychological resilience of patients with intermittent breast cancer chemotherapy was constructed,and the construction program was modified and improved through expert consultation.2.Formed an interdisciplinary working group with breast cancer nurses and software developers to jointly develop the psychological resilience mini program(1.0)and the management background for patients with intermittent breast cancer chemotherapy according to the established program.3.8 patients with intermittent chemotherapy for breast cancer and 4 nurses specializing in breast cancer were invited to use and evaluate the psychological resilience mini program(1.0)and the management background of patients with intermittent chemotherapy for breast cancer,including two parts: system test and In-depth interview.According to the evaluation results,the mental resilience mini program(2.0)for patients with intermittent chemotherapy for breast cancer was iteratively developed on the basis of the mental resilience mini program(1.0).4.A quasi-experimental study design was adopted to recruit intermittent breast cancer chemotherapy patients according to the inclusion and exclusion criteria,with40 patients in the intervention group and 40 patients in the control group.Patients in the control group received routine discharge care and follow-up,and patients in the intervention group received psychological resilience mini-program for patients with intermittent breast cancer chemotherapy on the basis of the control group(2.0).Patients’ data were collected before intervention(T0),3 months after intervention(T1)and 6 months after intervention(T2),and repeated measure analysis of variance was used to compare the scores of mental resilience,anxiety and depression,social support,quality of life and self-efficacy of the two groups.Results1.Form the development scheme of psychological resilience small program and management background for patients with intermittent chemotherapy for breast cancer,including category Ⅰ,Ⅱ,Ⅲ,Ⅳ items and specific function description.2.Completed the development of mental resilience mini program(1.0)and management background for patients with intermittent breast cancer chemotherapy.Mental resilience mini program for breast cancer patients in intermittent chemotherapy(1.0)contains five functional modules: "Information","interaction","mindfulness","management" and "My".Management background includes "patient management","ask experts","program editing" and "data statistics" four plates.3.The highest score,lowest score and average score of the Patient System Availability Scale(SUS)were 97.5,65 and 78.75;The highest score of SUS was 90,the lowest score was 62.5,and the average score was 76.875,indicating that the mental resilience mini program(1.0)in patients with intermittent chemotherapy for breast cancer had high availability.The results of in-depth interview showed that the mental resilience mini program(1.0)had beautiful page,simple operation and easy to use,and patients were willing to use it actively.Based on the evaluation results,this study cooperated with software developers to complete the iterative development of mental resilience mini program(2.0)for patients with intermittent breast cancer chemotherapy on the basis of mental resilience mini program(1.0).4.Study results of mental resilience mini program(2.0)in patients with intermittent chemotherapy for breast cancer(1)At T1 stage,1 case withdrew from the intervention group and 3 cases lost contact with the control group;In the T2 stage intervention group,1 case withdrew and 2 cases lost contact,and 2 cases lost contact in the control group.A total of 71 patients,36 in the intervention group and 35 in the control group,finally completed the study.(2)Before intervention(T0),there were no significant differences in general information,mental resilience,anxiety and depression,social support,quality of life,total score of self-efficacy and scores of each dimension between the two groups(P >0.05).(3)Psychological resilience: At the 3rd month after intervention(T1),the total score of psychological resilience in the intervention group was 67.58±11.41,which was higher than that in the control group(62.09±10.18)(P < 0.05).At the sixth month after intervention(T2),the total score of the intervention group was 68.75±9.34,which was higher than that of the control group,66.43±9.14(P > 0.05).Repeated measurement analysis of variance showed that the time effect and interaction effect of the total score of mental resilience in the two groups were statistically significant(P <0.05),while the intergroup effect was not statistically significant(P > 0.05).(4)Anxiety and depression: at the 3rd month after intervention(T1),the total score of anxiety and depression in the intervention group was 11.78±1.476,which was lower than that in the control group(15.86±1.54)(P < 0.05).At the 6th month after intervention(T2),the total score of anxiety and depression in the intervention group was 9.69±1.51,which was lower than that in the control group(12.03±1.42)(P< 0.05).Repeated measurement analysis of variance showed that the time effect,intergroup effect and interaction effect of the total score of anxiety and depression in the two groups were statistically significant(P < 0.05).(5)Social support: At the 3rd month after intervention(T1),the total score of social support in intervention group was 46.86±4.34,which was lower than that in control group(48.89±5.76)(P > 0.05).At 6 months after intervention(T2),the total score of social support in the intervention group was 46.97±4.16,which was lower than that in the control group(48.83±5.29)(P > 0.05).Repeated measures analysis of variance showed that the time effect of total social support was statistically significant(P < 0.05),while the intergroup effect and interaction effect were not statistically significant(P > 0.05).(6)Quality of life: At the third month after intervention(T1),the total score of quality of life in the intervention group was 92.25±12.55,which was higher than that in the control group(90.09±12.11,P > 0.05).At 6 months after intervention(T2),the total score of quality of life in the intervention group was 94.22±11.02,which was higher than that in the control group(91.11±11.41,P > 0.05).Repeated measures analysis of variance showed that the time effect of total quality of life in the two groups was statistically significant(P < 0.05),while the intergroup effect and interaction effect were not statistically significant(P > 0.05).(7)Self-efficacy: At the 3rd month after intervention(T1),the total score of the intervention group was 42.36±3.59,which was higher than that of the control group(39.23±4.90)(P < 0.05).At 6 months after intervention(T2),the total score of self-efficacy in the intervention group was 43.22±3.17,which was higher than that in the control group(42.06±4.22)(P > 0.05).Repeated measure analysis of variance showed that the time effect and interaction effect of the total score of self-efficacy in the two groups were statistically significant(P < 0.05),while the intergroup effect was not statistically significant(P > 0.05).Conclusions1.Psychological resilience mini program for patients with intermittent chemotherapy for breast cancer has strong usability and practicability.2.The mental resilience intervention based on M-health(mobile health)can improve the anxiety and depression of breast cancer patients during intermittent chemotherapy,improve their mental resilience and self-efficacy,and promote the improvement of patients’ quality of life. |
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