Analysis Of Risk Factors Of Preeclampsia Severity And Pregnancy Outcome

Objective:By analyzing the clinical data of patients with different severity of preeclampsia and maternal and infant outcomes,to explore the high risk factors affecting the severity of preeclampsia and pregnancy outcome.Methods:a retrospective analysis on January 1,2007 to December 31,2021 in shanxi medical university first hospital childbirth of the clinical data of 775 cases of maternal,divided into no severe preeclampsia group(MPE group,228 cases)and associated with severe preeclampsia group(SPE group,547 cases),The general data,pregnancy complications and maternal and infant outcomes of the two groups were analyzed.Results:(1)Comparison of general data: the median gestational age of delivery was 35 weeks in the SPE group and 38 weeks in the MPE group.The rate of caesarean section termination and irregular birth detection in the SPE group was higher than that in the MPE group,and the difference was statistically significant(P < 0.05).(2)Comparison of pregnancy complications: The proportion of SPE group with diabetes,delayed insulin release,hypothyroidism,subclinical hypothyroidism and hypocalcemia was higher than that of MPE group,and the difference was statistically significant(P < 0.05).(3)Comparison of adverse maternal pregnancy outcomes: The comprehensive prevalence of placental abruption,cardiac insufficiency,hypoproteinemia and HELLP in SPE group was higher than that in MPE group,with statistical significance(P < 0.05).(4)Comparison of perinatal adverse pregnancy outcomes: the proportion of neonatal asphyxia and stillbirth in SPE group was higher than that in MPE group,the difference was statistically significant(P < 0.05).(5)Multivariate analysis: diabetes mellitus,delayed insulin release,hypothyroidism,subclinical hypothyroidism,hypocalcaemia and irregular prenatal examination were risk factors affecting the severity of preeclampsia(P < 0.05).Conclusion:(1)Due to the serious condition of severe preeclampsia,the pregnancy is usually terminated by cesarean section,and the incidence of premature birth is high.Therefore,in clinical work,the timing of delivery should be balanced to achieve the maximum benefit of mother and child.(2)Pregnant women with gestational diabetes mellitus,delayed insulin release,clinical and subclinical hypothyroidism,and hypocalcemia are more likely to develop into severe preeclampsia.More attention and treatment should be given to pregnant women with these diseases during the prenatal examination to avoid the occurrence of severe preeclampsia as much as possible.(3)The irregular birth rate of pregnant women with severe preeclampsia is high,so the community and obstetricians should do a good job in education and management,so as to do a good job in the second-level prevention of the disease.