| Research objective: Through the collection of clinical information of atopic dermatitis patients of different ages,the constitution and TCM syndrome distribution of atopic dermatitis patients of different ages were analyzed,and the relationship between gender,age,severity of disease,laboratory indicators,lesion site,lesion characteristics and age,constitution and syndrome type was studied.Data support and theoretical basis for prevention and treatment of atopic dermatitis of different ages and protection of patients with different constitutions and syndromes can be provided by mastering the distribution law of constitution and syndrome types of patients with atopic dermatitis of different ages.Research methods: A total of 320 patients with atopic dermatitis in the outpatient and inpatient departments of the Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine from January 2022 to January 2023 who met the criteria were included in the questionnaire survey.The questionnaire mainly included epidemiological data,disease severity,skin rash site,skin lesion characteristics,TCM constitution and syndrome type assessment.The data were compiled,input,collate and generated by Excel 2019 form,and were transferred to SPSS25.0 database file for statistical analysis.Pearson 2 test was used for comparison between the two groups.t test was used for measurement data,corrected t test was used for variance variance,Wilcoxo rank sum test was used for non-normal distribution,and Wilcoxon rank sum test or Ridit analysis was used for rank data.SPSS25.0 statistical software was used for analysis.Research result:1.A total of 320 cases of atopic dermatitis were collected,of which 189 were males,accounting for 59.06%,and 131 were females.The age range was 7~75 years old,the mean age was 22.11±11.09 years old,and the median age was 24.5 years old.The onset age was mainly 12~45 years old(the younger group).The shortest course of AD was 0.6 years,and the longest was 40 years,the average course of disease was5.2±4.17 years,and the cases were mainly concentrated in 1-5 years.2.The constitution of 320 AD patients from high to low is: Characteristic quality(96 cases,30.0%)>dampness-heat quality(73 cases,22.81%)> phlegm-dampness quality(64 cases,20.0%)> Yin deficiency quality(39 cases,12.19%)> Yang deficiency quality(23 cases,7.19%)> Qi deficiency quality(10 cases,3.13%)> peace quality(7 cases,2.19%)> blood stasis quality(5 cases,1.56%)>Qi-stagnation(3 cases,0.94%).The incidence of AD was mainly biased constitution.3.The distribution of syndrome types in 320 AD patients from high to low was: syndrome of dampness-heat accumulation(119 cases,37.19%)> syndrome of heart fire and spleen deficiency(97 cases,30.31%)> syndrome of spleen deficiency and dampness-sheng(19.06%)> syndrome of blood deficiency and wind-dryness(13.44%);Region,climate,constitution,age and gender have influence on the syndroms.The syndroms of dampness-heat accumulation in males are more than those in females.The proportion of syndroms of blood deficiency and wind-dryness in > 45 years old(senior group)is significantly higher than that in ≤45 years old(younger group).4.Among the 320 patients with AD,189 were in the younger group and 131 were in the older group.The frequency distribution of age groups was 12~45 years old(105 cases,32.81%),6~12years old(84 cases,26.25%),and 45~60 years old(77 cases,24.06%)≥6。5.Based on SCORAD score,the frequency distribution of severity of disease was moderate from high to low(25 ~ 50)146 cases,45.63%;112 cases(35.0%)were mild(1-24 points);62 cases(19.38%)were severe(21~13 points).The severity of AD was still mild to moderate.6.The scalp and neck of the children group were preferred(41 cases,48.81%),the trunk of the adolescent and adult group was preferred(47 cases,25.82%),and the limbs of the elderly group were preferred(27 cases,50.0%),indicating that the scalp and neck of different age groups were different.Research conclusion:(1)Clinical data: AD has obvious familial tendency,long average course of disease and long age span.(2)Constitution distribution: the frequency of traditional Chinese medicine constitution of AD patients collected in this topic is in order of characteristic quality > damp-heat quality >phlegm-dampness quality > Yin deficiency quality > Yang deficiency quality > peace quality >blood stasis quality > Qi stagnation quality.AD is mainly biased constitution,and age,course of disease and syndrome type all have an effect on constitution.(3)Distribution of syndrome types: heart fire and spleen deficiency syndrome was the main syndrome in children with AD.Teenagers and adults with AD mainly syndromes of dampness-heat accumulation;Elderly AD is mainly characterized by blood deficiency and wind-dryness syndrome.Gender,age,constitution,disease degree and course all have influence on syndrome type.(4)Age distribution: Among the 320 patients with AD,the frequency distribution was 12~45 years old,6~12 years old,45~60 years old,≥60 years old.There were 189 cases in the younger group and 131 cases in the older group.The incidence of AD was still mainly in the younger group,mainly in the 12~45 years old. |
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