| Objective: To investigate the clinical efficacy and safety of full spine endoscopic transforaminal lumbar interbody fusion FE-TLIF for the treatment of lumbar spinal stenosis and instability(LSSI).instability LSSI).METHODS: A total of 68 patients treated with FE-TLIF and traditional open transforaminal lumbar interbody fusion Open-TLIF in the Department of Spine Surgery,Chifeng Hospital from December 2020 to March 2022 were selected.The experimental group consisted of 33 patients treated with the FE-TLIF technique.Thirty-three patients were treated with FE-TLIF as the experimental group and 35 patients were treated with Open-TLIF as the control group.Pre-and post-operative interleukin-6,interleukin-10,creatine kinase and C-reactive protein expression levels,Oswestry Disability Index scores,visual analogue scores for back pain,visual analogue scores for leg pain,preand post-operative intervertebral space height,intervertebral foramen height,segmental anterior convexity angle and lumbar anterior convexity angle were collected from patients in both groups.Length of hospital stay,surgical blood loss,operative time,number of intraoperative exposures,postoperative drainage,complication rate and intervertebral fusion and modified Mac Nab score at 12 months postoperatively were compared to follow-up data to assess surgical outcomes.RESULTS: All cases included in this study were followed up at 1year postoperatively.The length of hospital stay,surgical blood loss,operative time,postoperative drainage,and pre-and postoperative C-reactive protein,serum creatine kinase,interleukin-6 and interleukin-10 biochemical parameters were compared between the two groups,with the FE-TLIF group outperforming Open-TLIF(p < 0.05).The preoperative and postoperative back pain visual analogue score,leg pain visual analogue score and Oswestry disability index scores were significantly lower in both groups(P < 0.05),while the preoperative and postoperative leg pain visual analogue score and Oswestry disability index scores were not statistically different between the two groups(P > 0.05).The number of exposures was significantly higher in the FE-TLIF group than in the Open-TLIF group(P <0.05).In terms of complications,there was one intraoperative dural tear in each of the FE-TLIF and Open-TLIF groups,and one postoperative incisional infection was found in the Open-TLIF group;both patients were treated symptomatically and discharged without discomfort.Conclusion: The FE-TLIF technique can achieve similar clinical efficacy as open surgery in the treatment of LSSI,while having the advantages of being safe,effective and minimally invasive,and can be used as an important means of LSSI treatment. |