| Objective: To explore the correlation between preoperative liver surface nodularity(LSN)score and postoperative remnant liver volume regeneration in patients with partial hepatectomy,in order to provide reference for the accurate formulation of preoperative operation plan,evaluation of the prognosis of hepatectomy and prevention of postoperative complications.Methods: The patients who underwent hepatectomy in the First Hospital of China Medical University from January 2019 to December 2021 were collected,and 56 patients with preoperative enhanced CT,CT examination 2 weeks and 6 months after operation and complete clinical data were included in the study.The LSN scores were calculated by MATLAB software.3D Slicer software was used to perform three-dimensional reconstruction of the liver and simulated resection of liver,calculate the liver related volume and regeneration index(RI).Spearman correlation analysis was performed on clinical variables,LSN scores and residual liver volume regeneration index after hepatectomy.Results: There was a moderate negative correlation between LSN score and regeneration index 2 weeks and 6 months after operation respectively r=-0.472、-0.472、-0.455,P<0.01;r=-0.528、-0.528、-0.517,P<0.001).When considering the parenchymal hepatic resection rate(PHRR),in the PHRR<30% group,there was a moderate negative correlation between LSN score and regeneration index 2 weeks and 6 months after operation respectively(r=-0.455、-0.455、-0.435,P<0.01;r=-0.312、-0.312、-0.302,P<0.05).In the group with PHRR≥30%,there was no correlation between LSN score and regeneration index 2 weeks after operation;while,there was a strong negative correlation between LSN score and regeneration index at 6 months after operation(r=-0.741、-0.741、-0.664,P<0.05).Conclusion: The results of this study show that the LSN score can predict the regenerative potential of remnant liver volume after hepatectomy,and the LSN score can be used as an indirect indicator of the regenerative potential of remnant liver volume after hepatectomy for the formulation of clinical treatment plans for patients who need to undergo partial hepatectomy. |
