Font Size: a A A

Relationship Between Lymph Node Pathological Characteristics And Prognosis In Oral Squamous Cell Carcinoma

Posted on:2024-07-27Degree:MasterType:Thesis
Country:ChinaCandidate:Z S SuFull Text:PDF
GTID:2544307085974639Subject:Oral medicine
Abstract/Summary:
Objective: To evalute the pathology patterns of lymph nodes and clinical features in oral squamous cell carcinoma,and to correlate them with recurrence and Overall survival.Methods: A total of 100 subjects were taken for the study.Individuals who were admitted by the The First Affiliated Hospital of Xinjiang Medical University from January 2017 to January 2021,and collect their datas.All the patients underwent extended resection of the local tumor and neck dissection in the first operation.OS used the Kaplan–Meier method with log-rank tests of differences.Prognostic factors associated with OS were assessed by univariate analyses using the Cox proportional hazards regression model.Results: A total of 100 patients were followed up,and 10 were lost.Among the 90 patients,11 cases(12.2%)had cervical lymph node metastasis and recurrence.A significant correlation of SH(P = 0.016)was found with occult neck metastasis in Multivariate Cox proportional hazards regression analysis.These findings indicate that assessment of the SH might be useful in prognostication for occult neck metastasis.Differentiation,N stage and clinical stage had influence on OS(P < 0.05)from the single factor survival analysis results.Smoking,lymph node metastasis(N≠0),SH remained significant factors in prediction of occult cervical lymph node metastasis,which result in higher of recurrence rate of cervical lymph node metastasis in OSCC patients.Conclusion: It is SH and cervical lymph node metastasis that lead to the recurrence of cervical lymph node metastasis in OSCC patients independently.Moreover,the SH is effective in allowing an accurate evaluation of the risk of occult neck metastasis.It is differentiation degree and N stage that lead to the death of patients in OSCC patients independently.
Keywords/Search Tags:OSCC, Prognosis, Lymph node, Morphology
Related items