| Objective: To observe the effect of ultrasonic-guided unilateral cervical vagus nerve block on Postoperation nausea and vomiting(PONV)and Perioperative Neurocognitive Disorders in(PND)patients undergoing thoracic and abdominal endoscopic surgery under general anesthesia.Methods: From January 2022 to July 2022,120 patients undergoing elective laparoscopic thoracic and abdominal surgery in the Affiliated Cancer Hospital of Xinjiang Medical University,with ASA grade I.-III.,aged 24-75 years,were selected and divided into experimental group(ultrasound-guided unilateral vagus nerve block group)and control group(general general anesthesia group)by random number table method.The experimental group underwent ultrasound-guided unilateral vagus nerve block in the neck 15 minutes before anesthesia induction,and observed and recorded the changes of blood pressure,heart rate and average arterial pressure before and after vagus nerve block 15 minutes.The control group observed and recorded the changes in blood pressure,heart rate and average arterial pressure during the same time induced by general anesthesia.The clock drawing test and auditory verbal learning test(AVLT)were performed on the day before and the day after surgery to evaluate the effect of vagus nerve block on patients’ cognitive function,and the use of analgesic drugs and antiemetic drugs,the occurrence and severity of PONV in the two groups were recorded from preoperative to postoperative.Results: Compared with the control group,the incidence of postoperative PONV in the experimental group was lower and there was a statistical difference(P<0.01).Severity was also lower(P < 0.05),and there was no significant difference in PND-related scores between the two groups(P> 0.05).Conclusion: Unilateral vagal nerve block of the neck guided by preoperative ultrasound can reduce the incidence and severity of PONV in patients undergoing thoracic and abdominal laparoscopic surgery under general anesthesia,without significant effect on PND. |