Dental implants have become the first choice for the treatment of missing permanent teeth without damage to adjacent teeth,stability,beauty and long-life span.TC4(Ti6Al4V)titanium alloy is often the preferred material for dental implants due to its excellent mechanical properties,corrosion resistance and biocompatibility.However,it has the disadvantages of biological abortion and excessive size,which often leads to the lack of bone fusion between implant and natural bone after dental implant,resulting in reduced life span or treatment failure.The macroscopic porous structure and surface modification with certain porosity can improve the biological performance of titanium alloy stent to some extent,which can accelerate the osseous fusion between dental implants and natural bone,and prolong the service life of dental implants.3D printing technology with metal provides a new personalized manufacturing method for dentistry,which can more quickly and conveniently use titanium alloy and other medical materials to make dental implants with porous structure.Macroscopic porous structure can reduce the stiffness of dental implants,thus reducing the bone resorption caused by titanium alloy implants due to “stress shielding” and extending the service life of the implants.But the porosity must be appropriate,or it will compromise its mechanical properties.Surface modification on the basis of the porous structure can enable the 3D-printed dental implants to have more satisfactory biological activity,then,it accelerates the osteogenesis of the implant interface and extends the service life of the implant.The main contents of this study are as follows:Chapter 1,research background introduction.Based on the existing reference materials,the research status of this topic is reviewed,and the characteristics and applications of dental implants,3D printed titanium alloy implants and surface modification are indicated.Chapter 2,conduct the structural design and finite element analysis of dental implants.According to the existing studies,the dental implant structure is designed to have a honeycomb porous structure to reduce the structural stiffness of the dental implant.Computer-aided design was used to conduct the structural design of dental implants and construct the structural model,while combining finite element analysis to verify whether the dental implants with porous structure meet the requirements of mechanical mechanics and biomechanics.Finite element analysis was performed using a combination of hypermesh and ABAQUS software.Finite element analysis showed that dental implants with body porosity of 30% showed the best performance in finite element analysis experiments and can meet the requirements of both mechanical mechanics and biomechanics.Chapter 3,dental implant preparation and surface modification.Dental implant samples were prepared by 3D printing technology and traditional processing methods,and the prepared dental implant samples were subjected to surface modification such as sandblasting,acid erosion and alkali erosion.Then,the surface structure of the implants was characterized by scanning electron microscopy,X-ray diffraction meter,water drop angle meter,and contetometer to study the surface characteristics of the dental implants obtained by different preparation methods and different surface modifications.The results showed that the surface modification produced different surface microstructures on the surface of the implant;the surface modified improved the hydrophilic surface of the implant.Chapter 4,studies the biocompatibility,osteogenic capacity and bioactivity of dental implants through in vitro calcium phosphate deposition experiments and cell culture experiments.RESULTS The surface-modified implants deposited more hydroxyapatite in the calcium phosphate deposition experiments,indicating that the surface modification promoted the hydroxyapatite deposition and improved the bioactivity of the dental implants.Compared with dense titanium alloy implants,titanium alloy dental implants with macroscopic porous structures promote cell proliferation and differentiation,with better biocompatibility and osteogenic capacity.Chapter 5,for the full text summary and research outlook.Through the research concluded that the macroscopic porous structure can improve the biomechanics of dental implants,macroscopic porous structure and surface modification can improve the biocompatibility and biological activity of titanium alloy dental implants,in the macro porous structure titanium alloy dental implants on the basis of surface modification,greatly improve the osteogenesis ability of dental implants.This improved method is expected to improve the service life of dental implants. |