| Objective: To observe the clinical effect of auricular point pressing Dou combined with Guipi Wan on insomnia with depressive state in college students(deficiency of heart and spleen)Methods: In this study,105 college students with insomnia with depressive state(18to 30 years old,gender not limited)were selected in line with the case standards,and the105 patients were randomly divided into auricular point pressing Dou group,Guipi Wan group and combined group by random number table method,with 35 cases in each group.Auricular point pressing Dou group was treated with auricular point(Shengate,sympathetic,endocrine,heart,liver,subcortical,spleen,body and mind)pressure dou treatment,Guipi Wan group was treated with oral Guipi Wan treatment,combined group was treated with auricular point pressing Dou combined with Guipi Wan treatment.All patients were observed continuously for 4 weeks.TCM syndrome scores,Pittsburgh Sleep Quality Index(PSQI),Hamilton Depression Scale(Hamilton Depression Scale)were compared before and after intervention in the three groups Scale,HAMD-17)to observe the therapeutic effect and conduct statistical analysis.Result:1.Analysis of basic data: Before intervention,there were no statistical differences in age,gender,specialty,PSQI score,HAMD-17 score,TCM syndrome score and sleep factor score among the three groups(P>0.05),is comparable.2.TCM curative effect and TCM syndrome score: After 4 weeks of intervention,TCM syndrome score was decreased in all three groups,combined group was significantly better than auricular point pressing Dou group and Guipi Wan group in improving TCM symptoms,and auricular point pressing Dou group was better than Guipi group in improving TCM symptoms,with statistical difference(P<0.05).In terms of TCM efficacy,the effective rate of combined group(90.62%)was significantly higher than that of auricular point pressing Dou group(69.7%)and Guipi Wan group(62.5%),and the difference was statistically significant(P<0.05)3.Sleep efficacy and PSQI score: After 4 weeks of intervention,the sleep of patients in all three groups improved,and PSQI score decreased compared with that before treatment.After statistical analysis,the effective rate of auricular point pressing Dou group was 60.6%,the Guipi Wan group was 59.4%,the combined group was 90.6%.Combined group was better than auricular point pressing Dou group and Guipi Wan group,and the difference was statistically significant(P<0.05).4.Depression efficacy and HAMD-17 score: After 4 weeks of intervention,all patients in the three groups had improved depressive mood and HAMD-17 score decreased compared with before intervention;In terms of depression effect,the effective rate of auricular point pressing Dou group was 72.7%,Guipi Wan group was 53.1%,the combined group was 87.5%.Combined group was better than Guipi Wan group(P<0.05).5.Scores of various sleep factors: After 4 weeks of intervention,the sleep factor scores of the three groups were decreased,and the combined was significantly better than the auricular point pressing Dou and Guipi Wan in improving sleep quality,sleep efficiency and daytime function,the difference was statistically significant(P<0.05),auricular acupoint pressure Dou was better than Guipi Wan on the improvement effect of daytime function,the difference was statistically significant(P<0.05)。6.Safety analysis: During the study period,only one patient in the auricular acupoint pressure bean group had slight local skin itching after auricular acupoint pressure,and the symptoms disappeared after the replacement of anti-allergy auricular acupoint patch,while the other patients did not have uncomfortable symptoms and signs.Conclusion:1.Auricular acupoint pressure bean,Guipi Wan,auricular acupoint pressure bean combined with Guipi Wan can improve the insomnia symptoms and the depression state of college students,and the combined effect is better.2.Auricular acupoint pressure bean,Guipi Wan,auricular acupoint pressure bean combined with Guipi Wan can improve the TCM syndrome scores of college students,reduce PSQI score and HAMD-17 score of college students with insomnia and depression,and the combined application of the two is better.3.Auricular acupoint pressure bean,Guipi Wan,auricular acupoint pressure bean combined with Guipi Wan can improve patients’ sleep quality,sleep time,sleep efficiency and sleep disorders,auricular acupoint pressure bean combined with Guipi Wan was superior to auricular acupoint pressure bean and Guipi Wan in improving patients’ sleep quality,sleep efficiency and daytime function,and auricular acupoint pressure bean was superior to Guipi Wan in improving daytime function.4.Auricular point pressing Dou combined with Guipi Wan in the treatment of insomnia with depression state of college students has good clinical effect,small side effects,is safe and effective. |