| ObjectiveThe purpose of this study was to use the software "Traditional Chinese Medicine Inheritance Assistance Platform(V2.5)" to explore the data of prescriptions of traditional Chinese medicine for treating insomnia,so as to deeply analyze the syndrome types,syndrome differentiation and clinical effects,and to provide effective reference and clinical ideas for the traditional Chinese medicine treatment of insomnia.Methods Medical records of 100 patients with insomnia were collected.General data,clinical data,syndrome differentiation and first prescription were collected.Data analysis methods such as association rule analysis method,improved mutual information method and complex system entropy clustering were implemented by the.software system of "TCM Inheritance Assistance Platform(V2.5)",combined with the Criteria for the Diagnosis and Efficacy of TCM symptoms,medical history materials of insomnia patients were processed by data,so as to deeply explore the medication characteristics and prescription rules of insomnia.To better evaluate its clinical efficacy.Result①In this study,a total of 100 insomnia patients were collected,including 24 males and 76 females,with a sex ratio of about 1:3.16.Significantly more of these patients are women than men.In terms of age,these people are mainly distributed between 46 and 69 years old,and middle-aged people are the most common group.In terms of syndrome type,phlegm-heat internal disturbance syndrome is the most typical.In terms of clinical symptoms,the most frequent symptoms were sleep disorders,bitter mouth,irritability,dry mouth,palpitation,early awakening,restlessness and fatigue,etc.,which was basically consistent with the clinical symptoms of phlegm-heat internal disturbance syndrome of high-frequency syndrome.In the aspect of tongue and pulse,there were 10 kinds of tongue,13 kinds of tongue coating and 12 kinds of pulse,among which the reddish tongue,thin coating and thin pulse were the most common.②After 8 weeks of treatment,the number of cured patients(9%)and effective patients(26%)increased significantly,and the overall effective rate reached 81%.③A total of 156 traditional Chinese medicines were involved in the prescription input in this study.and the total frequency of medication was 1619 times.In terms of drug properties,cold,flat and warm drugs are the most common.In the aspect of medicinal taste,sweet.bitter and occinative are the most commonly used;In the aspect of drug channel conversion,the heart and liver channels are mainly involved,and other menstrual drugs are also involved.④Based on the analysis of prescription rules based on association rules,273 groups of commonly used drug combinations were obtained,including 24 Chinese medicines,and the top five groups were bupleurum bupleurum and jujube seed,respectively;Licorice,sour jujube kernel;Licorice,bupleurum;Sour jujube kernel,night rattan;Licorice,poria cocos.Down-regulation of the number of support obtained that the drug combination contained 10 traditional Chinese medicines,which were glycyrrhiza,sour jujube kernel,bupleurum bupleurum,nightsweeten rattan,poria cocos,scutellaria scutellaria,alacia bark,pinellia pinellia,oyster and radix polygonae.Conclusion ① Traditional Chinese medicine has unique clinical advantages in treating insomniacs,which can improve insomnia symptoms and improve sleep time.②The core drugs obtained in this study were glycyrrhiza licorice,sour jujube kernel,bupleurum bupleurum,nocturnae rattan,poria cocos,Scutellaria scutellaria,albizia bark,pinellia pinellia,Oyster and Radix polygonae.③The disease is located in the heart and liver,and the main syndromic types are phlegm-fire disturbing the heart and Yin deficiency and fire-growth syndrome.The main syndromic elements are fire,phlegm and Yin deficiency,followed by qi stagnation.In the treatment of insomnia,we should combine the syndrome differentiation of Qi,blood,body fluid and zang fu organs,with phlegm,fire and qi as the main line,and the heart,liver and spleen as the purpose,and adopt the methods of clearing fire,eliminating phlegm and regulating qi,so as to achieve the purpose of harmonizing Yin and Yang,calming the spirit and helping sleep. |