| Objective:By comparing the body weight,hemoglobin,total protein,food intake(eating frequency,number of meals,number of meals)of patients with gastric cancer after total gastrectomy with regulatory dual digestion channel reconstruction(R-Dcr)and Roux-en-Y(RY)reconstruction Changes in indicators such as food intake),intestinal pressure,etc.,to further explore the changes of postoperative intestinal pressure and its impact on the quality of life in patients who underwent total gastrectomy and gastrointestinal reconstruction after total gastrectomy.The choice of formula provides objective basis and scientific reference.Methods:A total of 40 patients with advanced gastric cancer who underwent total gastrectomy in Sichuan Mianyang 404 Hospital between November 2019 and November 2020 were included as the research subjects,and were randomly grouped using the envelope method.Groups were reconstructed using Roux-en-Y.Inclusion criteria:(1)18-70 years old;(2)no radiotherapy,chemotherapy or immunotherapy before surgery;(3)no medical or surgical diseases affecting the patient’s digestion and absorption;(4)in line with the indications for total gastrectomy;(5)Patients voluntarily participate and cooperate in clinical research and sign relevant consent forms.Exclusion criteria:(1)history of intra-abdominal and gastrointestinal surgery;(2)metabolic disorders such as diabetes and hyperthyroidism;(3)pregnant women and lactating women;(4)other types that do not meet the indications for total gastrectomy Gastric cancer;(5)Mental illness cannot cooperate with the experimenter.The gender,age,body weight,hemoglobin,total protein,tumor diameter and clinical stage of the two groups of patients were compared;the intestinal pressure of the patients 6 months after the operation was measured and recorded;the total protein,hemoglobin and body weight of the patients 6 months after the operation were recorded;The incidence of postoperative complications(such as dumping syndrome,regurgitation,belching,upper abdominal fullness,etc.)and the daily food intake and frequency of eating 6 months after the operation;completed the questionnaire 6 months after the operation,and analyzed the statistics and analysis.Quality of life of patients at 6 months postoperatively.Results:There was no significant difference in age,gender,body weight,hemoglobin,total protein,tumor diameter,and clinical stage of the tumor between the two groups before surgery(P>0.05).The postoperative intestinalpressure values of both the study group and the control group were lower than the normal level,but the study group was closer to the normal level than the control group,and the difference between the two groups was statisticallysignificant(P<0.05).The incidence of postoperative belching,upper abdominal fullness and regurgitation in the study group was less than that in the control group,and the difference was statistically significant(P<0.05).There was no statistical difference in postoperative anastomotic leakage and dumping syndrome between the two groups.academic significance(P>0.05).Six months after the operation,the body weight of both groups decreased,and the hemoglobin and total protein decreased to varying degrees,and the decrease in the study group was lower than that in the control group(all P<0.05).The daily food intake of the study group was greater than that of the control group 6 months after surgery,and the number of daily meals was more than that of the control group(all P<0.05).In a quality of life statistical analysis,the study group’s physical,emotional,and overall health scores were higher than those in the control group 6 months after surgery(all P<0.05),but the scores of the two groups in other functional areas and symptom areas were higher than those of the control group(all P<0.05).The difference between them was not statistically significant(all P>0.05).Conclusion:1.The intestinal pressure after regulated double-channel interposition jejunal digestive tract reconstruction is closer to the normal physiological level than that of Roux-en-Y reconstruction;2.The adjusted double-channel interposed jejunal digestive tract reconstruction is more effective after total gastrectomy The improvement of quality of life was more obvious than that of Roux-en-Y reconstruction. |
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