Correlation Analysis Of TCM Syndrome Distribution And Nutritional Status,Inflammatory State In AECOPD

Objective: To retrospectively analyze the medical records of 233 AECOPD patients,collect general information,TCM syndromes,and laboratory indicators related to inflammatory state and nutritional status,study the distribution of AECOPD syndrome types,and explore the correlation between laboratory indicators and AECOPD syndrome types.Methods: Using the Lianzhong electronic case system,patients with AECOP who were hospitalized in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine from January 2020 to January 2021 and met the inclusion and exclusion criteria were selected,and their medical records were retrospectively studied.Data collection Patient name,age,gender,TCM diagnosis and syndrome type,white blood cell count(WBC),lymphocyte percentage(L%),neutrophil percentage(NE%),platelet count(PLT),red blood cell distribution width(RDW)),particle to lymphatic ratio(NLR),blood to lymphatic ratio(PLR),serum prealbumin(PA),serum albumin(ALB),triglyceride(TG),serum total protein(TP),cholesterol(TC),Hemoglobin(Hb),body mass index(BMI)results.Data were recorded and a database was established,and all data were statistically analyzed using SPSS 26.0 statistical software.Results: A total of 233 samples were included in this study,including 174 male samples and 59 female samples.Taking the age difference of 15 as a stage,there are 72samples(30.90%)between 51-65 years old,124 samples(53.22%)between 66-80 years old,and 37 samples(15.88%)between 80-94 years old.Among the 233 samples,56 cases of phlegm turbidity syndrome,50 cases of phlegm and blood stasis syndrome,46 cases of phlegm-heat accumulation syndrome,29 cases of outer cold and inner drink syndrome,28 cases of yang deficiency syndrome,24 cases of lung and kidney qi deficiency syndrome.example.The average age of external cold and internal drink syndrome was 70.14±9.395 years old,the average age of phlegm and blood stasis obstruction lung syndrome was 71.58±8.303 years old,the average age of phlegm heat accumulation syndrome was 71.04±7.315 years old,the average age of phlegm turbidity obstruction lung syndrome was 70.29±8.604,the average age of lung-kidney qi deficiency syndrome was 73.04±10.54 years old,and the average age of yang-deficiency-water syndrome was 74.25±8.792 years old.AECOPD different syndrome types WBC,PLT,NLR,ALB,NE%,L%,TC,PA level P<0.05,the difference is statistically significant significance.After multiple comparisons after the event,it was found that there was a statistical difference between the groups(P<0.05): the levels of WBC,NLR and NE% in the syndrome of phlegm-heat obstructing the lung were higher than those of other syndromes,and the L% level was the lowest in the syndrome of phlegm-heat obstructing the lung.The L% level of Hannei Yin syndrome was the highest,the level of PLT in phlegm-heat obstructing lung syndrome and phlegm stasis lung syndrome was higher than that of other syndromes,and the levels of PA and ALB in yang deficiency and water syndrome were lower than those of other syndromes.The levels of PLR,RDW,Hb,TP,TG,and BMI have no correlation with different syndrome types of AECOPD,while the highest level in lung syndrome.Conclusion:1.The incidence of AECOPD is higher in males than in females.AECOPD is dominated by syndromes mixed with deficiency and excess,with phlegm-heat obstructing the lung syndrome,phlegm-turbidity-obstructing lung syndrome,and phlegm-stasis-obstructing lung syndrome accounting for the main part.2.AECOPD TCM syndrome types are correlated with WBC,NE%,PLT,NLR,ALB,PA,L%,and TC,as well as the specific manifestations are: higher levels of WBC,NE%,PLT,NLR and lower levels of L% It can assist in the diagnosis of phlegm-heat obstructing the lung syndrome;low levels of WBC,NE%,NLR,and L% are related to lung-kidney qi deficiency and yang-deficiency-water syndrome.Phlegm obstruction lung syndrome related.Low levels of ALB,PA,and TC are related to the syndrome of yang deficiency and water,meanwhile if WBC and NE% are not significantly elevated,it can assist in the diagnosis of phlegm and blood stasis obstruction of the lung syndrome.3.The average levels of RDW,TG and BMI in each syndrome type are in the normal range,the RDW of yang deficiency syndrome and the lung-kidney qi deficiency syndrome are higher,but TG and BMI are lower.The Hb level of the generalized syndrome of Yang deficiency and water was lower than the lower limit of normal,and the Hb levels of the other five syndromes were all within the normal range.The TP levels of all syndrome types were lower than the lower limit of normal,and the most obvious was the generalized syndrome of yang deficiency and water.The level of PLR is higher in the syndrome of phlegm and blood stasis obstructing the lung and the syndrome of stagnation of phlegm and heat.