| Objective:To explore the correlation between obstructive sleep apnea hypopnea syndrome and changes in olfaction,and provide a reference for the study of clinical olfaction.Methods:This study will be 131 participants according to the results of polysomnography were divided into observation group(OSAHS group)and control group(OSAHS group),respectively on two groups of lines of olfactory function Test(Korean version of the olfactory Test Ⅱ bar,the Korean Bersion of Sniffin Sticks Test(KVSS Test Ⅱ)),according to the sense of smell test results it is concluded that in patients with OSAHS dysosmia risk and disease severity and light,medium and severe hypoxemia relation with the sense of smell,The correlation of olfactory threshold,olfactory recognition and olfactory cognition between the observation group and the control group was further analyzed.Result:1.There were no statistically significant differences in age,gender,education level and smoking history between the observation group and the control group.In addition,there was no statistically significant difference in age between the observation group and the control group(Z=0.412,P=0.686).The duration and BMI of patients with and without OSAHS were not statistically significant(Z=-0.287,P=0.774)(t=1.097,P=0.276)in the observation group,and the age of mild,moderate and severe OSAHS patients in the observation group was not statistically significant(Z=4.483,P=0.106).2.The incidence of olfaction disorders was significantly different between the observation group and the control group(x2=12.000,P=0.001).3.There was no statistical difference(P=1.000)between the observation group and the control group in the probability of the occurrence of anosmia disorder(i.e.,anosmia and anosmia),but anosmia was dominant in both groups.4.The incidence of olfaction disorders in severe OSAHS patients was significantly higher than that in mild patients(P<0.05),and the proportion of OSAHS patients with olfaction disorders increased with the increase of OSAHS severity(x2=10.672,P=0.001).5.OSAHS patients with osmia disorder had significantly lower mean oxygen saturation and lowest oxygen saturation than those without osmia disorder(P<0.001).6.There were statistically significant differences in the severity of hypoxemia between patients with obstructive sleep apnea hypopnea syndrome(osmia)and those without osmia(osmia)(P<0.01).The incidence of moderate hypoxemia in the group without osmia was higher than that in the group with osmia(P<0.05),while the incidence of severe hypoxemia was lower than that in the group with osmia(P<0.05).7.KVSS between two groups of Test II total score no statistical difference(t=1.166,p=0,249),the sense of smell recognition scores also no statistical difference(t=1.5988,p=0.116),but the olfactory threshold score(t=5.3469,p<0.001)and olfactory recognition score(t=6.405,p<0.001)there were significant differences between the two groups.Conclusion:1.OSAHS has a negative effect on olfaction,and the severity of the disease is positively correlated with the incidence of olfaction.2.The olfactory dysfunction that occurs in OSAHS is mainly hyposmia,and it is mainly manifested by a decline in olfactory cognitive score.3.People with OSAHS with olfactory disorder have lower minimum and average blood oxygen saturation,and those with olfactory disorder often have severe hypoxemia,and those without olfactory disorder often have moderate hypoxemia. |
