Preparation And Performance Study Of MXene-PNIPAm-based Smart Responsive Hydroge

In recent years,with the rapid development of science and technology,flexible wearable devices have also emerged and developed rapidly.Flexible wearable devices are emerging in endlessly.Smart watches and smart wristbands have become a mainstream trend and are widely used in the field of medical and health monitoring.With the advent of the 5G era,people’s needs have become diversified,and there is a higher demand for the intelligence of flexible wearable devices.Smart hydrogel dressings require high stretch,compression elasticity and flexibility,as well as other kinematic properties,such as strong skin adhesion,and the ability to attach complex curved surfaces and dynamic objects.Current hydrogel devices usually have a single function and cannot meet the application requirements of smart hydrogel dressings.Therefore,it is necessary to conduct good real-time monitoring of the dynamic environment of wound tissues and control the release of drugs as needed.In this research,we developed a new smart hydrogel dressing based on conductive MXene nanosheets and temperature-sensitive PNIPAm polymer.Select γ-methacryloxypropyltrimethoxysilane(KH570)to further functionalize the surface of MXene to improve the interface compatibility between MXene and PNIPAm.The prepared K-M/PNIPAm hydrogel has strain-sensitive characteristics and response to NIR phase change and volume change.When used as a strain flexible sensor,this KM/PNIPAm hydrogel exhibits high strain sensitivity,with a strain factor(GF)of 4.491,a wide working strain range of ≈250%,a fast response speed of about 160 ms,and good cycle stability(Cycle for 3000 seconds at 20% strain),which can be used to monitor larger body movements and smaller pulses.In addition,this K-M/PNIPAm hydrogel can be used as an efficient near-infrared light controlled drug release carrier to achieve ondemand drug delivery.And showed good biocompatibility in cytotoxicity and skin implantation tests.Smart hydrogel dressings may have great potential in the practical application of real-time human health monitoring and drug release control.