Research And Implementation Of Whole Slide Images Storage And Sharing Scheme Based On Blockchain

Pathological slides are of great significance to clinical diagnosis and pathological research.The emergence of whole slide images improves the efficiency of pathologists and provides new directions for remote pathological diagnosis and AI medical assistance research.However,centralized storage and medical privacy leaks have caused whole slide images to form data islands in medical institutions,hindering the further development of whole slide imaging.The development of blockchain technology provides new ideas for data storage and sharing.The advantages of decentralization and non-tampering make it used in the fields of digital currency,commodity traceability,and medical security widely.Hyper Ledger Fabric is an open-source alliance blockchain platfo rm which is a framework for blockchain-based applications.Based on blockchain technology,this paper do a deep research on how to improve the security,privacy,value of sharement in the process of WSI storage and sharing,and finally implement the system on that.First,this paper making an intensive study on the Raft: a consensus algorithm used in consortium blockchains widely,then propose a method called Adaptive Multi-Request and Recommend Candidate to avoid multiple elections in Raft and speed up the election of cluster leaders.After that,this paper propose WSI storage sharing scheme.According to the structural characteristics of the WSI,Converting WSI in difference format into dcm by downsampling and image cutting,This helps separates the WSI image data from the sensitive data,and get standard dcm files and WSI digests.The WSI digests and shareable wsi digests are stored in distributed ledger on blockchain separately.The dcm files are stored in the off-chain IPFS files storage system.The decentralized storage ensures the WSI data security.identity verification are protected by algorithm(EC DSA)and data on blockchain are encrypted in symmetric encryption algorithm(AES).The key of AES are sent to researcher after encrypted in public key in asymmetric encryption algorithm(RSA).The safety of the scheme is analyzed and compared with the existing scheme.Finally,combining all above studies,this paper designd and implement a WSI storage and sharing system.The system adopts a browser \server architecture,uses Hyperledger Fabric as the underlying blockchain network framework,and user data is stored in the relation database Mysql,and interacts with the Fabric network through the Hyperledger Fabric SDK for Java tool.The back end system is developed using Spring Boot+Java+Mybatis framework,and the web page is developed using Vue.js.The four modules of user login,data access,data upload,and request sharing were introduced,and after that tested the system functions.