Research On The Activation And Functional Connection Of Sound Information In Human Brain

The pattern and spatial information of sound is thought to be processed in the ventral and dorsal pathways in the brain,respectively.Although the dual-pathway model is widely accepted,the degree of independence between the two streams is still controversial,and another widely distributed network model has been proposed.In order to further explore the processing mechanism of sounds and reveal the brain regions affected by different frequencies and directions,we selected sounds with different frequencies and directions as the stimulus materials,and adopted the experimental paradigm of block design,and then collected the task-state data of 28 subjects by using functional magnetic resonance imaging(f MRI).Using a combination of univariate analysis and functional connectivity analysis,we explored the brain areas that were affected by activation and functional connections when the sound was performed at different frequencies and directions.The results of univariate analysis revealed that the sound with different frequencies mainly affected the superior temporal gyrus,and the low frequency had a greater impact on this area.The activation of the direction condition resulted in a phenomenon of contralateral activation in the superior temporal gyrus.The results of the functional connection analysis showed that the sounds in different frequencies mainly affected some brain regions in the default mode network(DMN),and different regions showed different responses to the frequencies,which reflected the function of DMN in collecting and evaluating the internal and external information.The functional connection of sound in different directions affected a widely distributed brain network and almost all significant regions showed significant differences between central and eccentric directions,while the sound from left and right were similar.The study demonstrated the effects of sound in different frequencies and directions in the brain from the results of both activation and functional connectivity,helping to reveal the processing mechanisms of sound information on frequency and direction in the brain.