| Purpose:1.Through meditation and stop party and consolidate plan the entire group(long-term)treatment,meditation stop treating symptoms disappear and partially completed the consolidation scheme(short-term I group),meditation stop treating symptoms disappear or withdrawal(short-term ? group),not regular taking meditation arresting party group(other)four groups of patients after 18 one full year of life condition,understanding of adult children with tic disorders,and life condition,evaluation of meditation snap forward curative effect.2.Through to the 18 years old later there is still a twitch symptoms in children with cross-sectional survey,a comprehensive understanding of existing twitch symptoms after 18 years of age,such as the weight of the twitch degree,whether to need to use again,if there are complications,etc.,for the early Chinese medicine treatment and prevention of recurrence.Methods:The cases in this subject are all from the outpatients of Dr.Han Fei,Department of Pediatrics,Guang'anmen Hospital,China Academy of Chinese Medical Sciences.Children with tic disorder who were 18 years old from 2010-1-1 to 2019-12-31 and who were 18 years old by 2020-12-31 were selected.Using retrospective research methods,self-compiled a series of questionnaires for children with TD after adulthood:"Personal Basic Information and First-diagnosed Incidence Questionnaire","Jingxin Zhidong Recipe Treatment and Consolidation Program Implementation Questionnaire","General Prognosis of Adulthood""Questionnaire" and all entered into the "Questionnaire Star" applet to make an online return interview form "Survey Form for Adult Status Quo of Children with Tic Disorders",and collect relevant information through telephone and WeChat return interviews.According to the Yale Comprehensive Tic Severity Scale(YGTSS),the patients were divided into the above-mentioned four groups and twelve levels,and the health status of the children in each group after adulthood was compared,so as to obtain the relevant factors affecting the adult prognosis,such as gender and grade of first-diagnosed disease.,Constitution type,early treatment status,comorbidities,taking of Jingxin Zhidong Recipe(course of treatment,length of consolidation period,etc.),family genetic history,etc.The data of patients who still have symptoms after 18 years of age will be further analyzed to see if there are general incentives,so as to better guide the prevention and treatment of adult patients with tic disorder.Results:1.In this study,a total of 641 valid interviews were collected,and 641 adult children with TD were finally included,including 526 males and 115 females,with a male-to-female ratio of 4.57:1.The age range of adult children with TD in this return visit was 18-28 years old.The results showed that the age range of children with TD was 3-18 years old,and the peak incidence was 8 years old.Regarding the first symptoms of the disease,70.83%of the children indicated that blinking symptoms were the main symptoms.All cases were classified according to the Yale scale at the time of first diagnosis,of which 431 cases were moderate(67.24%),143 cases were mild(22.31%),and 67 cases were severe(10.45%).Chi-square test was performed between the grading of the first-visit Yale Scale and whether there was a family genetic history(P>0.05),and the results showed that the samples of different first-visit Yale Scale grading did not show a significant difference in whether there was a family genetic history,and there was no statistical significance..Chi-square test(cross-over analysis)was used to study the effect of Yale scale grading on EEG abnormalities in the newly diagnosed Yale scale.The results showed that the Yale scale grading samples at first diagnoses were significant(p<0.05)for EEG abnormalities,which was statistically significant.2.The long-term group included 137 adult children with TD,accounting for 21.37%;the short-term group I included 68 cases,accounting for 10.61%;the short-term group ? included 115 cases,accounting for 17.94%;the other groups included a total of 321 cases,accounting for 50.08%.128 children with long-term TD have no recurrence at present,accounting for 93.43%of the total number of cases in this group,only 8 currently have recurrence,accounting for 5.84%of the total number of cases in this group;48 cases in the short-term group I currently have no recurrence,accounting for this group 70.59%of the total number of cases in the group,6 people currently have recurrence,accounting for 8.82%of the total number of cases in this group;92 cases in the short-term group ? currently have no recurrence,accounting for 80%of the total number of cases in this group,and 13 people are currently experiencing recurrence.Accounted for 11.30%of the total number of cases in this group.Among children diagnosed with mild TD at the first diagnosis,24.28%had tic symptoms in adulthood;62.69%of severe TD children had tic symptoms in adulthood;46.40%of moderate TD children still had tic symptoms in adulthood.3.There were 275 cases of Jingfang treatment until the tic symptoms disappeared and no recurrence after adulthood,accounting for 42.9%of the total number of cases included in this study.Among the 275 children with no recurrence after adulthood,86 were diagnosed with mild TD(31.27%),176 were moderate(64%),and 13 were severe(4.73%).101 children(36.73%)had received other treatments before Jingfang treatment.128 children completed the complete treatment plan during the Jingfang treatment.The length of the Jingfang treatment for 128 children was statistically described.The maximum value was 120 months,the minimum value was 12 months,and the median was 36 months.Of the children treated with Jingfang until their symptoms disappeared without recurrence in adulthood,128 cases were included in the long-term group,92 cases were included in the short-term group I,28 cases were included in the short-term group ?,and only 7 cases were included in the other groups.4.Twenty-nine children were treated with Jingfang until their symptoms disappeared and relapse after adulthood,accounting for 4.5%of the total number of cases included in this study.There were 23 children with moderate grades on the Yale scale,accounting for 79.31%of the total number of children with recurrence after adulthood,4 children with mild cases,accounting for 13.79%,and 2 children with severe cases,accounting for 6.9%.During the follow-up visit,it was found that the average age of first recurrence of children with recurrence in adulthood was 18.38 years old.Word cloud graph analysis of 29 children with recurrent TD after adulthood showed that blinking,throat clearing,facial twitching,eye squeezing,and head movement were the main symptoms of recurrent tics.Among the possible recurrence factors,the highest proportion is higher education/work pressure,followed by physical overwork,and the influence of mental stimulation/emotional changes should also not be underestimated.The Yale scale was used to classify children with relapsed TD after adulthood.There were 28 mild children,accounting for 96.55%,and the proportion of moderate and severe children was extremely low.Thirteen cases were included in the short-term group 2,6 cases were included in the short-term group 1,only 8 cases were included in the long-term group,and the other groups included a total of 2 cases.5.A total of 337 children still had tic symptoms at the end of the Jingfang treatment.After adulthood,there were 277 children with tic symptoms,accounting for 82.2%,and 60 cases without tics,accounting for 17.8%.A statistical analysis of the current tic symptoms of 277 children who still had tic symptoms in adulthood found that the most common tic symptoms in adulthood were throat clearing,vocalization,eye movements,mouth movements,and hand movements.Adult children with TD were graded by the Yale Scale in 218 cases of mild cases,of which 202 cases have not taken any treatment,accounting for 92.66%of the total number of mild cases;38 cases of moderate cases,of which 34 cases have not been treated,accounting for medium 89.47%of the total number of severely affected children;7 severely affected children,2 of which took treatment measures.Among the adult children with TD who still have tic symptoms,18 children have comorbidities after adulthood.As for the factors related to tic symptoms in children with TD in adulthood,nervousness,overwork,and excessive use of electronic products were mentioned frequently during the return visit.Conclusion:1.Meditation arresting party complete treatment scheme(treatment period consolidate period),which can effectively reduce the adulthood twitch symptoms and recurrence of tic disorders.2.Adulthood in children with recurrent relapse in average age of 18.38 years for the first time.3.Children with abnormal electroencephalogram(eeg)is associated with both the illness severity 4.Early intervention,Chinese traditional medicine can effectively reduce the adulthood twitch symptoms 5.Very few children in adulthood twitch symptoms are severe,occur at the same time 6.Combined with the conditions and related influencing factors of adulthood complications,TD adult children should take more attention in terms of emotion regulation,so as to reduce the occurrence of twitch symptoms and recurrence of tic disorders.7.Children's mental health for tic disorders and prognosis of disease have a certain influence... |
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