Application Value Of Color Doppler Blood Flow Parameters In Intrauterine Hypoxia Of Fetus With HDCP

Objective:To investigate the Doppler hemodynamic changes and clinical value of umbilical artery（UA）,middle cerebral artery（MCA）and renal artery（RA）in pregnantwomen with hypertensive disorder complicating pregnancy（HDCP）,so as to provide basis for clinicians to diagnose fetal intrauterine hypoxia and take reliablemeasures,Prevent adverse events and ensure the safety of mothers and infants.Material and Methods:127 pregnant women in the third trimester,aged 20-45 years and 31-41 weeks of gestation,who were filed and examined in our hospital from January to December2020 and delivered successfully in our hospital,were randomly selected.They were divided into hypertension group（63 cases）and healthy control group（64cases）according to whether there was HDCP.Routine obstetric ultrasound examination was performed with ultrasonic Doppler diagnostic instrument,andthen the Doppler ultrasound blood flow imaging data of all fetuses were collected by color ultrasonic Doppler technology.The pulsatility index（PI）,resistance index（RI）,peak systolic blood flow velocity / end diastolic blood flow velocity（S/ D）of UA,MCA and RA were compared between the two groups,The ratio of MCA to UAresistance index,i.e.cerebral–placental ratio（CPR）,and the ratio of MCA to RA resistance index,i.e.cerebral–renal ratio（CRR）,were calculated and compared between the two groups.The related indexes of newborns in the two groups wererecorded.Results:1.The PI,RI and S / D values of fetal MCA in hypertension group were lower than those in healthy control group,and the PI,RI and S / D values of UA and RA werehigher than those in healthy control group,and the difference between the two groups was statistically significant（P < 0.05）.2.The fetal cerebral–placental ratio and cerebral–renal ratio in the hypertension group were lower than those in the healthy control group,and the differencebetween the two groups was statistically significant（P < 0.05）.3.In the diagnosis of fetal intrauterine hypoxia with gestational hypertension,thearea under the ROC curve of UA and MCA PI,RI and S/D is slightly higher than that of RA and the sensitivity of RA PI,RI and S / D is higher.The overall sensitivity andspecificity of multi parameter joint detection are high.4.The results of 1-minute Apgar score and neonatal weight in healthy controlgroup were significantly better than those in hypertension group（P < 0.05）.Conclusion:1.The monitoring of fetal umbilical artery,middle cerebral artery and renal artery hemodynamics is an important index to predict fetal intrauterine hypoxia inpregnancy induced hypertension.2.The area under the ROC curve of umbilical artery and middle cerebral artery isslightly higher than that of renal artery,and the sensitivity of renal artery is higher.3.The combined detection of umbilical artery,middle cerebral artery and renalartery has high overall sensitivity and specificity.It can make a more comprehensive judgment on the fetal intrauterine condition,comprehensively reflect the maternal placental fetal circulation state,early and timely find theintrauterine hypoxia of HDCP fetus and predict the adverse pregnancy outcome,so as to provide a basis for clinicians to intervene in advance To provide a reliablebasis for reducing the rate of perinatal fetal defects.