Ultralong Hydroxyapatite Nanowires And Silane Assembling Into Enamel-like Dental Restorative Materials

Objective: Dental defects are the most common oral clinical disorder,and enamel itself cannot regenerate.So,it can only be repaired with artificial materials.While various materials on the market always have various deficiencies for various reasons.The purpose of this research in this topic is to create a restorative material that can structurally resemble enamel to improve the deficiencies of commercially available materials.Methods:The composite was composed of hydroxyapatite nanowires and silane coupling agent-kh570.Hydroxyapatite nanowires were synthesized by calcium oleate precursor solvothermal method and act as an inorganic component in the composite.KH 570 were organic component which can rely on self-polymerization and silane coupling to bring together the organic-inorganic components.Then the material is densified by cold isostatic pressing technology.The basic properties and morphology of hydroxyapatite nanowires and their composites were characterized by X-ray diffraction（XRD）,scanning electron microscopy（SEM）and Fourier transform infrared spectroscopy（FTIR）.The microhardness,radial tensile strength（DTS）,compressive strength（CS）and friction and wear data of composites and other control materials were tested,and the obtained data were statistically analyzed by analysis of variance（ANOVA）.At the same time,the cell compatibility experiment also shows that the material has good cell compatibility and meets the non-toxic requirements of oral repair materials.Results:We have successfully synthesized ultra-long hydroxyapatite nanowires,and used these nanowires as inorganic raw materials to successfully synthesize enamel like dental repair composites containing 72% inorganic components.The rigorous mechanical property test results show that the composite has good mechanical properties.The microhardness of the composite is higher than that of the three common after-sales tooth filling resins.There is no statistical difference between the compressive strength and the two.Although the radial tensile strength is slightly lower,the statistical results show that there is no difference between the composite and the two.The rigorous mechanical property test results show that the composite has good mechanical properties.The microhardness of the composite is higher than that of the three common after-sales tooth filling resins.There is no statistical difference between the compressive strength and the two.Although the radial tensile strength is slightly lower,the statistical results show that there is no difference between the composite and the two.At the same time,the cell compatibility experiment also shows that the material has good cell compatibility and meets the non-toxic requirements of oral repair materials.Conclusion:The characterization and cytocompatibility showed the composite had a good comprehensive performance,and provided new ideas and directions for dental restorations...