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Global Acute Coronary Registration Score Combined With TNI Peak To Predict The Cardiac Function In Patients With Acute Myocardial Infarction

Posted on:2022-06-18Degree:MasterType:Thesis
Country:ChinaCandidate:H F ChengFull Text:PDF
GTID:2504306743983659Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective: In this paper,by studying the GRACE score joint TNI peak and the correlation of patients with AMI after PCI with early postoperative cardiac function,thus clear the value of GRACE score and TNI peak to early predict cardiac function in patients with AMI.Methods: By selecting 292 cases of the people who were suffering from acute myocardial infarction for the first time,according to the examination results of each case at admission,through Grace score they were divided into three groups: low risk group,middle risk group and high risk group;and according to the peak value of TNI during hospitalization they were divided into three groups.Monitoring 292 cases of patients with acute myocardial infarction after they were treated with PCI,the BNP of early(within 24 hours),echocardiography suggested LVEF and whether patients were treated with diuretics during hospitalization.One-way ANOVA using multiple groups of counting data to compare each groups’ LVEF and BNP;a non-parametric test for comparing the date which include the utilization rate and dosage of diuretics;using the Spearman correlation analysis to analyse the relativity between GRACE score and TNI peak.Results:1 According to the GRACE score cases are divided into three groups,for three groups of compared LVEF.There were statistically difference between the three groups(P<0.05);2 According to the GRACE score cases are divided into three groups,then comparing the BNP of three groups.The differences between the low risk group and high-risk group;the middle risk group and high risk group,two sets of data between a statistically significant difference(P < 0.05).But the difference between low risk group and high risk group didn’t have statistical significance(P>0.05);3 The use of diuretics among GRACE scoring groups was pairwise compared.The differences among low risk group and high risk group,middle risk group and high-risk group had statistical significance(P<0.0125).But the difference between low risk group and middle risk group didn’t have statistical significance(P>0.0125);4 By TNI peak is divided into three groups and compared their LVEF.There was no significant difference between A group and B group(P>0.05).There have statistical sense among the A group and C group,B group and C group(P<0.05);5 BNP was compared between the three groups which are divided through TNI peak.The results showed that there were no differences in pairwise comparison among the three groups(P>0.05);6 The three group are divided according to TNI peak,the utilization rate of diuretics among the three groups was pairwise compared.There didn’t have any statistical significance between A group and B group,B group and C group(P>0.0125).But the utilization rate of diuretics among the A group and C group,there was a significant difference between them(P<0.0125);7 Comparisons between the GRACE high-risk group along with the TNI peak obviously elevate group and the total sample’ s LVEF,the GRACE score high-risk group,the LVEF in TNI peak significantly elevated group,BNP and the utilization rate of diuretics.All the groups but the date of BNP and LVEF were statistically significant(P<0.05),the BNP and LVEF of the groups didn’t have statistical significance(P>0.05);8 All the incidences of the GRACE score and the TNI peak didn’t obey normal distributions.Thus evaluate the relationship between the two variables through the spearmen correlation analysis,result showed that the two variables were positively correlated,and correlation coefficients were 0.311(P<0.05).Conclusion:1 The GRACE score can well differentiate the low risk patient and the high risk patient who was suffering from AMI,that can make treatment programs more individualized.Hoping to improve the living quality and long-term prognosis of patients with cardiac function,and decrease the possibility which may make them become the patients with chronic heart failure;2 The TNI peak also can provide reference about the early cardiac risk stratification function for patients who were suffered from acute myocardial infarction;3 The combination of GRACE score and TNI peak to some extent can better predict the patients’ early partial cardiac function after acute myocardial infarction.
Keywords/Search Tags:acute myocardial infarction, global registry of acute coronary event risk score, cardiac troponin Ⅰ peak, chronic heart failure
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