Clinical Research Of Yin-yang Tiao Li Moxibustion Combined With Ear-point Pressing Beans For The Treatment Of Perimenopausal Insomnia

ObjectiveThe main purpose is to analyze the clinical efficacy of Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans therapy for the treatment of perimenopausal insomnia.The secondary purpose is to compare with simple ear acupuncture,discussing the clinical superiority of Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans in the treatment of perimenopausal insomnia,providing new methods and new ideas for the treatment of this disease.MethodsIn this research,patients with perimenopausal insomnia who were treated in of Acupuncture and Moxibustion Department of Hubei Provincial Hospital of Traditional Chinese Medicine from June 2020 to December 2021 were selected as the research subjects and randomly divided into 2 groups.30 women were in the group of Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans,and the rest in simple ear acupuncture group.The simple ear acupuncture group received ear-point pressing beans therapy.The auricular acupoints are hendocrine,subcortex,Shenmen,consensus,liver,spleen,kidney and heart.Then press selected auricular acupoints 3～5times a day,each 1～2 minute.Alternate treatment from each auricula to another was implemented and the auricular sticker was changed once every other day.3 times a week,2 weeks as a course of treatment,a total of 4 courses of treatment was conducted.In addition to ear-point pressing beans therapy,a Yin-Yang Tiao Li moxibustion was further provided to the group of integrated therapy of Yin-Yang Tiao Li moxibustion and ear-point pressing beans therapy.It mainly selects Wenyang Yishen moxibustion and Peiyuan Guben moxibustion in the Yin-Yang Tiao Li moxibustion.Wenyang Yishen moxibustion is to apply moxibustion in a circle with a radius of 8 to 10 cm centered on Mingmen acupoint,and Peiyuan Guben moxibustion is to apply moxibustion in a circle with a radius of8 to 10 cm centered on Shenque acupoint.Yin-Yang Tiao Li moxibustion was conducted once a week,60 minutes once time.2 weeks as a course of treatment,a total of 4 courses of treatment was conducted.Before and after treatment,PSQI scores,SPIEGEL scores,modified Kupperman scores,and HAMA scores from patients in 2 groups were recorded and analyzed,thereby valuating the efficacy and safety of Yin-Yang moxibustion combined with ear-point pressing beans therapy for this disease.Results（1）In comparison with baseline information: A total of 60 women patients with perimenopausal insomnia were included in this study,and there is no dropouts in both groups.Of which,30 women were in the group of Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans,and the rest in simple ear acupuncture group.Also,there were no statistically significant difference in ages,the course of disease,and other aspects（P>0.05）,so the two groups are comparable.（2）In comparison with clinical efficacy: The total effective rate（93.33%）of the Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans group was obviously better than that of the simple ear acupuncture group（80.00%）,and the difference was statistically significant（P<0.05）.（3）In comparison with PSQI scores: After treatment,each factor score of PSQI and the total score in two groups were obviously reduced,and the differences before and after treatment were significant（P<0.05）.Between groups,no matter from the total scores of PSQI or from score sleep quality,sleep time and day function,the Yin-Yang Tiao Li moxibustion plus ear-point pressing beans group was obviously lower than the simple ear acupuncture group,and differences between two groups were significant（P<0.05）.（4）In comparison with SPIEGEL scores: After treatment,the SPIEGEL scores were lower than those before treatment in two groups,and differences before and after treatment were significant（P<0.05）.Between groups,the SPIEGEL scores of the Yin-Yang Tiao Li moxibustion plus ear-point pressing beans group was obviously lower than that of the simple ear acupuncture group,the difference was statistically significant（P<0.05）.（5）In comparison with modified Kupperman scores: After treatment,the modified Kupperman scores were cut down in two groups,and the difference before and after treatment were statistically meaningful（P<0.05）.Between groups,the modified Kupperman scores of the Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans group was obviously lower than that of the simple ear acupuncture group,and difference between two groups was significant（P<0.05）.（6）In comparison with HAMA scores: After treatment,the HAMA scores were lower than those before treatment in two groups,and there was a statistically meaningful difference before and after treatment（P<0.05）.Between groups,the HAMA scores of the Yin-Yang Tiao Li moxibustion plus ear-point pressing beans group was obviously lower than that of the simple ear acupuncture group,and the difference was statistically significant（P<0.05）.（7）Safety evaluation: There is no major adversity during this clinical study.During the treatment period,only 3 patients had slight scald at the place of abdomen in the group of Yin-Yang Tiao Li moxibustion combined with ear-point pressing beans,which were recovered after routine treatment.No sequelae were left.There was no adverse effects in the simple ear acupuncture group.Conclusion（1）Yin-Yang Tiao Li moxibustion and ear-point pressing beans combination and simple ear acupuncture therapy can both effectively treat female perimenopausal insomnia,but Yin-Yang Tiao Li moxibustion and ear-point pressing beans combination has better clinical efficacy.（2）Compared with the therapy of ear-point pressing beans,Yin-Yang Tiao Li moxibustion and ear-point pressing beans combination has better curative effect in improving patients’ sleep quality,sleep time,day function,degree of insomnia,perimenopausal-related symptoms and anxiety,and it is worthy of further promotion in clinical work.