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The Effect Of Remote Ischemic Postconditioning On Acute Cerebral Infarction In Anterior And Posterior Circulation

Posted on:2022-07-14Degree:MasterType:Thesis
Country:ChinaCandidate:C Y LiuFull Text:PDF
GTID:2504306575479864Subject:Neurology
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Objectives To compare the different effects of remote ischemic postconditioning on the curative effect and short-term prognosis of acute cerebral infarction in anterior and posterior circulation,understand the difference of curative effect of remote ischemic adaptation in the treatment of acute anterior and posterior circulation,to provide further guidance for clinical treatment.Methods A total of 171 cases of acute brain infarction were collected in the second area of neurology and the fourth neurology zone of the Affiliated Hospital of the North China University of Technology from April 2019 to October 2020.According to the standard OCSP server profile divided into two groups namely forward contain 88 cases and backward rounds contain 83 cases.The two groups were given basic treatment according to the 2018 acute standardized treatment of acute ischemic cerebrovascular disease in China,all patients were given Remote ischemic postconditioning based on this treatment.The whole course of treatment is seven days.Note the NIHSS and ADL values for 3,7 and 30 days before and after the intervention.Use NIHSS to assess the patient’s neurological defects and ADL to assess the patient’s daily life capacity.Analyze the effectiveness of NIHSS scores from both patient groups and explore the different effects of limb separation on the therapeutic effectiveness of patients with cerebral infarction before and after an acute cycle.Results 1 NIHSS scores for both groups of patients are in constant decline before treatment,3,7 and 30 days after treatment.Perform statistical analysis of the data using a repetitive measurement variance analysis,the differences in interaction between the two groups,at different times and between groups and at different times are statistically significant(P<0.05).2 The difference between NIHSS levels prior to treatment is statistically meaningless.(F=0.637,P>0.05).The results of the contrast of the NIHSS scores of 3,7 and30 days after the acceptance of the RIPost C intervention are as follows(F=9.421,P<0.05),(F=37.475,P<0.05),(F=54.016,P<0.05),the differences are statistically distinct.3Differences between NIHSS scores at different times in both patient groups before and after the RIPost C intervention are statistically significant(P<0.05).4 The two groups have different tendencies to lower NIHSS scores at the same time,however,both showed that the decline in NIHSS scores was greatest when adaptation interventions lasted 3 to 7 days after the limbs were removed.5 ADL scores for both groups of patients are in constant incline before treatment,3,7 and 30 days after treatment.Perform statistical analysis of the data using a repetitive measurement variance analysis,the differences in interaction between the two groups,at different times and between groups and at different times are statistically distinct(P<0.05).6 The ADL score difference before treatment for 2 groups of patients is not statistically significant(F=2.712,P>0.05).The results of the comparison of the NIHSS scores of 3,7 and 30 days after the acceptance of the RIPost C intervention are as follows(F=11.354,P<0.05),(F=25.037,P<0.05),(F=28.608,P<0.05),the differences are statistically clear.7 Differences between ADL scores at different times in both patient groups before and after the RIPost C intervention are statistically significant(P<0.05).8 The two groups have different tendencies to higher ADL scores at the same time,however,both showed that the decline in ADL scores was greatest when adaptation interventions lasted 3to 7 days after the limbs were removed.9 In the anterior circulation group,there has 7 cases were basically cured,50 cases were significant progress,21 cases were progress,9 cases were invalid and1 worsen,explicit efficiency was 67%,total effective rate was 89%;In the posterior circulation group,there has 6 cases were basically cured,33 cases were significant progress,24 cases were progress,17 cases were invalid,3 cases were worsen,explicit efficiency was 45%,total effective rate was 76%.It was statistically distinct to compare two groups of notable and overall performance indicators(P<0.05),The front circulating group is much more efficient and efficient than the rear.Conclusions 1 Remote ischemic adaptation has a better therapeutic effect on patients with acute brain infarction in the OCSP subgroup.The effect of pre-acute myocardial infarction is even greater.2 The therapeutic effect of post-ischemic adaptation on people with acute cerebral infarction is most evident when the procedure lasts 3 to 7 days.Figure 2;Table 10;Reference 128...
Keywords/Search Tags:acute cerebral infarction, remote ischemic postconditioning, Oxfordshire community stroke project OCSP, therapeutic effect
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