Assessment Of Left And Right Ventricular Strain Values In Patients With Pulmonary Hypertension By Cardiac Magnetic Resonance Tissue Tracking

Objective: By utilizing the cardiac magnetic resonance(CMR)tissue tracking technique,the left and right ventricular strain parameters of pulmonary hypertension(PH)patients were analyzed retrospectively;the study investigated the correlations between left and right ventricular strain,as well as the ventricular strain changes during cardiac function preservation among pulmonary hypertension patients.Method: Conventional heart scan film sequences in 65 cases of PH patients and 32 cases in the control group were collected;the cardiac function parameters and strain parameters of left and right ventricles were obtained via the post-processing by CVI 42 software;the left and right ventricular strain parameters in the global PH group as well as the ventricular strain among PH patients with cardiac function preservation were analyzed,respectively;between-group mean value comparison,Spearman correlation coefficient analysis and interclass correlation coefficient(ICC)were applied.Result: The global radial strain,circumferential strain and longitudinal strain of left and right ventricle in the PH group were analyzed by tissue tracking technique and the repeatability was preferable(ICC≥0.75).The global radial strain,circumferential strain and longitudinal strain of left and right ventricle in the PH group compared with the control group had significant differences.The global radial strain of left and right ventricle in the PH group presented moderate correlation(r=0.487,p<0.01),the circumferential strain of left and right ventricle presented moderate correlation(r=0.437,p<0.01),while the longitudinal strain of left and right ventricle had no statistical correlation.As for the 14 cases of PH patients with right ventricular function preservation,the global radial strain,circumferential strain and longitudinal strain of right ventricle had significant differences compared with the control group[(16.79±5.31)%vs(23.33±7.98)%,(-13.36±4.23)%vs(-20.08±6.41)%、(-10.28±3.00)vs(-13.30±4.23)%,p<0.01];while the global circumferential strain for basal of right ventricular had no remarkable differences.For the 39 cases of PH patients with left ventricular function preservation,only the longitudinal strain of left ventricle had significant differences compared with the control group[(-14.16±3.04)%vs(-16.79±2.86)%,Z=-3.444,p<0.01];the global and partial radial strain and circumferential strain of left ventricle had no remarkable differences.Conclusion: The cardiac magnetic resonance(CMR)tissue tracking technique is able to present quantitative evaluation for the left and right ventricular strain parameters for pulmonary hypertension patients,moreover,it has preferable feasibility and repeatability;the global radial strain and circumferential strain of left and right ventricle presents moderate correlation;the longitudinal strain of left and right ventricle had no apparent correlation;the global strain of three directions among PH patients with right cardiac function preservation had no remarkable differences compared with the control group;the global longitudinal strain among PH patients with left ventricle cardiac function preservation has significant differences compared with the control group.