Comparative Study On The Efficacy Of Direct Interventional Therapy And Thrombolysis Combined With Interventional Therapy In Elderly Patients With Acute ST Segment Elevation Myocardial Infarction

Objective: To compare the efficacy of direct interventional therapy and thrombolysis combined with interventional therapy in elderly patients with acute ST segment elevation myocardial infarction.Methods: The elderly STEMI patients who were admitted to the chest pain Center of the second Hospital of Hebei Medical University and underwent emergency coronary angiography(CAG)from December 2018 to December 2020 were included as the observation subjects,and the patients who were directly admitted to our hospital for emergency PCI(PPCI)were selected as the control group(60 cases).The patients who were referred to our hospital for early PCI(EPCI)after intravenous thrombolysis in the local hospital were selected as the experimental group(24 cases).The differences of clinical efficacy and safety between the two groups were compared.Results: The time from onset to reperfusion,BNP,thrombus score,TIMI grade 0 and the proportion of heart failure in the test group were significantly lower than those in the control group.LVEF,TIMI grade 3,postoperative TIMI grade 3 and TMPG grade 3 in the test group were significantly higher than those in the control group,and there was significant difference between the two groups.Conclusions: EPCI can improve the blood flow of elderly patients with STEMI before and after operation,reduce the infarct size,improve cardiac function and reduce the incidence of adverse events during hospitalization,and there is no increase in the risk of bleeding in this study.For hospitals that can not carry out emergency PCI,it is recommended to choose the comprehensive treatment strategy of intravenous thrombolysis combined with PCI.