| Objective:18F-DCFPy L-labeled PSMA PET/CT is an internationally advanced nuclear medicine imaging technique for the diagnosis of prostate cancer.The purpose of this study was to preliminarily compare the detection efficacy of 18F-DCFPy L PET/CT and multi-parameter nuclear magnetic resonance imaging（MRI）in prostate cancer,and to evaluate the correlation between the maximum standard uptake value of prostate cancer foci and the malignancy degree of prostate cancer.Methods:By retrospective analysis during may 2019 to September 2020 in Shanxi Bethune hospital nuclear medicine line 18F-DCFPy L PET/CT examination of the clinical data of 27patients,comparing mp-MRI and 18F-DCFPy L PET/CT for the detection of prostate cancer and the ability of T stage,comparison the difference of the medium-risk group and the high-risk group stratification SUVmax value,evaluates SUVmax ISUP classification and grouping,prostate specific antigen（PSA）and the correlation of Gleason score.Results:For newly diagnosed prostate cancer patients,18F-DCFPy L PET/CT detection rate was significantly higher than that of mp-MRI（96.30%vs.74.07%,P=0.031）.In the 20patients detected by MP-MRI,18F-DCFPYL PET/CT and MP-MRI had the same T staging in 18 cases,with a high similarity（Kappa coefficient 0.84,P<0.001）.The SUVmax value in the high-risk group was significantly higher than that in the medium-risk group（P=0.005）.There was a moderate correlation between SUVmax and ISUP classification（r=0.587,P=0.01）.There was a strong correlation between SUVmax and Gleason score（r=0.622,P=0.01）,and a weak correlation between SUVmax and PSA（r=0.380,P=0.05）.Conclusion:18F-DCFPy L PET/CT may be better than mp-MRI in the detection of newly diagnosed prostate cancer,but the similarity of T staging ability is very high.SUVmax value may have a good ability to distinguish patients in the middle and high risk groups,and is positively correlated with the degree of malignancy of prostate cancer,which has a high predictive value. |
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