Relationship Between Metabolic Syndrome And New Onset Atrial Fibrillation After Acute Myocardial Infarction

Objective:To study the relationship between metabolic syndrome(MS)and new onset atrial fibrillation(AF)after acute myocardial infarction(AMI).Methods:a total of 721 patients with AMI admitted to Shanxi cardiovascular hospital or the second hospital of Shanxi Medical University from January 2019 to December 2019 were collected and divided into MS group(n=322)and non MS group(n=399).Baseline data,echocardiographic indexes and incidence of atrial fibrillation were compared between the two groups.Then,patients were divided into AF group(n=48)and non AF group(n=673)according to presence of AF.The relationship between MS components and AF is explored.Results:Compared with the non MS group,the patients in the MS group had higher body weight,BMI,fasting blood glucose,systolic pressure,diastolic pressure,admission heart rate,triglycerides(TG),low-density lipoprotein cholesterol(LDL-C)and uric acid levels,and lower age and high-density lipoprotein cholesterol(HDL-C)levels,the incidence of combined hypertension,diabetes mellitus,inferior wall infarction and three-vessel lesion was higher,the diameter of left atrium and left ventricle was larger,the difference was statistically significant(p<0.05),the left atrial diameter was the largest and the incidence of AF was the highest at MS 4 points.The enlargement of left atrium was independently associated with the occurrence of AF after AMI(p<0.05,OR=1.165,95%CI:1.051-1.291).Compared with the non AF Group,the AF group was older,had higher admission heart rate,fasting blood glucose,neutrophil ratio,Alanine aminotransferase(ALT)level,and had worse cardiac function,the difference was statistically significant(p<0.05),in which fasting blood glucose was independently associated with AF(p<0.05,OR=1.102,95%CI: 1.011-1.201).Conclusion:Fasting blood glucose in MS is an independent risk factor for AF after AMI,and MS can increase the occurrence of AF after AMI by causing changes in cardiac structure and function.