| Objective:Inflammatory bowel disease(IBD)is composed of a set of repeated recurrence nonspecific inflammatory disease,gastrointestinal tract into ulcerative colitis(UC)and crohn’s disease(CD),the undifferentiated colitis(IC),UC and CD are its main types,this article USES the meta-analysis research abdominal intestinal ultrasound(TBUS)value to the diagnosis of recurrence of IBD.Methods:The following 8 databases were searched by computer in Chinese and English,including PubMed,The Cochrane Library,Web of Science and Embase,and CBM,CNKI,Wanfang Data and VIP in Chinese.Two reevaluators independently searched and screened all the TBUS diagnostic trials on recurrence of IBD from the establishment of the database to February 2021 according to the inclusion and exclusion criteria,and evaluated the diagnostic accuracy and quality of the finally included literatures and extracted relevant data.Data extracted from the final included studies were combined and statistically analyzed using Meta Disc 1.4,Rev Man5.3 and Stata 14.0 software.Results:A total of 9 studies were included,with the total sample size of 481 cases,UC sample size of 106 cases,CD sample size of 375 cases,through research on the degree of sensitivity,specific,positive likelihood ratio(PLR),negative likelihood ratio(NLR)and diagnostic odds ratio,and through the combined numerical and its 95% confidence interval and SROC area under curve(AUC)to evaluate TBUS on recurrence of IBD diagnosis efficiency.Results of Meta analysis are as follows:1.The IBD group: the combined sensitivity was 0.82(95%CI:0.77-0.86),the combined specificity was 0.59(95%CI:0.52-0.66),the combined PLR was 1.96(95%CI:1.07-3.57),the combined NLR was 0.37(95%CI:0.21-0.65),the combined DOR was 6.27(95%CI:1.87-21.10),the AUC was 0.80,the Q index was 0.78;2.The UC group: the combined sensitivity was 0.87(95%CI:0.77-0.94),the combined specificity was 0.83(95%CI:0.64-0.94),the combined PLR 4.71(95%CI:2.20-10.06),the combined NLR 0.17(95%CI:0.09-0.30),the combined odds ratio DOR=29.56(95%CI:9.15-95.48),AUC=0.93,and Q index =0.86;3.The CD group: the combined sensitivity was 0.80(95%CI:0.73-0.85),the combined specificity was 0.55(95%CI:0.48-0.63),the combined PLR was 1.83(95%CI:1.07-3.12),the combined NLR was 0.39(95%CI:0.23-0.68),the combined diagnostic odds ratio DOR was 5.73(95%CI:1.78-18.46),the AUC was 0.83,and the Q index was 0.77.Conclusion:1.TBUS has the advantages of being non-invasive,convenient,well tolerated and non-radiation,and has a medium diagnostic efficiency for the recurrence of IBD.It has certain guiding significance for the initial diagnosis of the recurrence of IBD,and can be used together with other examinations to judge the activities of IBD;2.The efficacy of TBUS in the recurrence diagnosis of UC and CD is not statistically significant,which may be related to the relevant examination equipment,the number of cases included in the study,the study design and other factors.Further study should be conducted to expect more accurate and reliable results. |
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