| Purpose:To investigate the clinical value of cardiovascular magnetic resonance tissue tracking(CMR-TT)in the assessment of right ventricular myocardial strain in patients with Hypertrophic Cardiomyopathy(HCM).Materials and Methods:Retrospective analysis was performed on 50 patients admitted to our hospital from August 2018 to May 2020 who were clinically diagnosed as hypertrophic cardiomyopathy,and 20 healthy controls.Among the patients with HCM,22 patients had right ventricular hypertrophy,and 28 patients did not have right ventricular hypertrophy.There were 31 patients with interadjoining enhancement and 19 patients without interadjoining enhancement.MRI plain and enhanced images were collected in the lesion group,and MRI plain images were collected in the control group.Cardiac magnetic resonance main sequence including ventricular short axis and four cavity fast imaging employing steady-state acquisition(FIESTA)film images;Ventricular short axis Inversion Recovery Fast Grass(IRFGR)delayed enhanced image.All the images by using post-processing software(cvi42,Circle Cardiovascular imaging,v.5.6,Calgary,AB,Canada)for processing.The software was used to track and calculate the deformation parameters of the right ventricle,The longitudinal peak strain(LPS),circumferential peak strain(CPS)and radial peak strain(RPS)of the whole and segmental myocardium of the right ventricle were included.And the strain rates(LSR,CSR,RSR)of the right ventricle at systolic and diastolic stages,and the time-strain and time-strain rate curves of the right ventricle were generated.The strain and strain rate differences between HCM and normal control group were analyzed and compared,and the parameters between each group and normal control group were compared according to the grouping.All measurement data using Kolmogorov Smirnov has test of normality test,accord with normal distribution with mean ± standard deviation(`x±s)said,compares the single factor analysis of variance between groups,compares the two independent sample t test.Enumeration data were presented as numbers,and P<0.05 was considered statistically significant.Results:The Global longitudinal strain of HCM group and normal control group were(-6.96±4.32;-9.73±3.08),the difference between the two groups was statistically significant(P =0.011).In right ventricular segmental myocardial analysis,the median ventricular LPS and RPS of HCM group and control group were(-5.45(-9.74,8.77);-8.90 ± 7.90),(56.92(37.87,86.76);61.9 ± 19.62),and there were statistical significance between the two groups(P =0.008,p=0.013).There were no significant differences in radial,circumferential and longitudinal strains between the enhanced group and the unenhanced group(P >0.05).In Right Ventricular hypertrophy(RVH)group and non RVH group,two groups of Global longitudinal strain(-5.50±4.27;-8.00±4.09)(43.6±17.94;60.8±32.78)was statistically significant(P =0.003),while the Global circumferential strain and radial strain of the two groups there were no statistical significance(P >0.05).Systolic longitudinal strain rate(SLSR)of RVH group,non-RVH group and control group(-0.64(-0.82,-0.31);-0.47(-0.78,-0.80);-0.78±0.29)there was statistical significance among the three groups(P =0.044).Conclusion:The right ventricular systolic function of patients with HCM was lower than that of normal control group,and the reduction of right ventricular function was more obvious in patients with right ventricular hypertrophy.CMR-TT can detect the RV myocardial changes in patients with HCM earlier than the reduction of RVEF,and the reduction of HCM myocardial strain with RVH is more significant. |
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